M. Airavaara, O. Pletnikova, M. E. Doyle, Y. E. Zhang, J. C. Troncoso et al., Identification of Novel GDNF Isoforms and cis-Antisense GDNFOS Gene and Their Regulation in Human Middle Temporal Gyrus of Alzheimer Disease, Journal of Biological Chemistry, vol.286, issue.52, pp.45093-45102, 2011.
DOI : 10.1074/jbc.M111.310250

P. A. Baecker, W. H. Lee, A. N. Verity, R. M. Eglen, and R. M. Johnson, Characterization of a promoter for the human glial cell line-derived neurotrophic factor gene, Molecular Brain Research, vol.69, issue.2, pp.209-222, 1999.
DOI : 10.1016/S0169-328X(99)00106-0

K. C. Caires, A. J. De, and D. J. Mclean, Endocrine Regulation of Spermatogonial Stem Cells in the Seminiferous Epithelium of Adult Mice, BioResearch Open Access, vol.1, issue.5, pp.222-230, 2012.
DOI : 10.1089/biores.2012.0259

D. De-cesare and P. Sassone-corsi, Transcriptional regulation by cyclic AMP-responsive factors, Prog. Nucl. Acid Res. Mol. Biol, vol.64, pp.343-369, 2000.
DOI : 10.1016/S0079-6603(00)64009-6

E. T. Dermitzakis and A. G. Clark, Evolution of Transcription Factor Binding Sites in Mammalian Gene Regulatory Regions: Conservation and Turnover, Molecular Biology and Evolution, vol.19, issue.7, pp.1114-1121, 2002.
DOI : 10.1093/oxfordjournals.molbev.a004169

J. Don and G. Stelzer, The expanding family of CREB/CREM transcription factors that are involved with spermatogenesis, Molecular and Cellular Endocrinology, vol.187, issue.1-2, pp.115-124, 2002.
DOI : 10.1016/S0303-7207(01)00696-7

L. Dovere, S. Fera, M. Grasso, D. Lamberti, C. Gargioli et al., The Niche-Derived Glial Cell Line-Derived Neurotrophic Factor (GDNF) Induces Migration of Mouse Spermatogonial Stem/Progenitor Cells, PLoS ONE, vol.60, issue.6, p.59431, 2013.
DOI : 10.1371/journal.pone.0059431.s002

URL : https://hal.archives-ouvertes.fr/pasteur-01053530

M. Galdieri, E. Ziparo, F. Palombi, M. A. Russo, and M. Stefanini, Pure Sertoli Cell Cultures: A New Model for the Study of Somatic-Germ Cell Interactions, Journal of Andrology, vol.159, issue.5, pp.249-254, 1981.
DOI : 10.1002/j.1939-4640.1981.tb00625.x

D. Gancz and L. Gilboa, Hormonal Control of Stem Cell Systems, Annual Review of Cell and Developmental Biology, vol.29, issue.1, pp.137-162, 2013.
DOI : 10.1146/annurev-cellbio-101512-122331

M. Grasso, A. Fuso, L. Dovere, D. G. De-rooij, M. Stefanini et al., Distribution of GFRA1-expressing spermatogonia in adult mouse testis, Reproduction, vol.143, issue.3, pp.325-332, 2012.
DOI : 10.1530/REP-11-0385

URL : https://hal.archives-ouvertes.fr/pasteur-00978700

L. Grimm, E. Holinski-feder, J. Teodoridis, B. Scheffer, D. Schindelhauer et al., Analysis of the human GDNF gene reveals an inducible promoter, three exons, a triplet repeat within the 3'-UTR and alternative splice products, Human Molecular Genetics, vol.7, issue.12, pp.1873-1886, 1998.
DOI : 10.1093/hmg/7.12.1873

M. D. Griswold, The central role of Sertoli cells in spermatogenesis, Seminars in Cell & Developmental Biology, vol.9, issue.4, pp.411-416, 1998.
DOI : 10.1006/scdb.1998.0203

K. Hasegawa, S. H. Namekawa, and Y. Saga, MEK/ERK signaling directly and indirectly contributes to the cyclical self-renewal of spermatogonial stem cells, STEM CELLS, vol.121, issue.11, pp.2517-2527, 2013.
DOI : 10.1002/stem.1486

Z. He, J. Jiang, M. C. Hofmann, and M. Dym, Gfra1 Silencing in Mouse Spermatogonial Stem Cells Results in Their Differentiation Via the Inactivation of RET Tyrosine Kinase1, Biology of Reproduction, vol.77, issue.4, pp.723-733, 2007.
DOI : 10.1095/biolreprod.107.062513

L. L. Heckert and M. D. Griswold, Expression of Follicle-Stimulating Hormone Receptor mRNA in Rat Testes and Sertoli Cells, Molecular Endocrinology, vol.5, issue.5, pp.670-677, 1991.
DOI : 10.1210/mend-5-5-670

M. C. Hofmann, Gdnf signaling pathways within the mammalian spermatogonial stem cell niche, Molecular and Cellular Endocrinology, vol.288, issue.1-2, pp.95-103, 2008.
DOI : 10.1016/j.mce.2008.04.012

D. S. Johnston, E. Olivas, P. Dicandeloro, and W. W. Wright, Stage-Specific Changes in GDNF Expression by Rat Sertoli Cells: A Possible Regulator of the Replication and Differentiation of Stem Spermatogonia1, Biology of Reproduction, vol.85, issue.4, pp.763-769, 2011.
DOI : 10.1095/biolreprod.110.087676

P. A. Joshi, D. Grappa, M. A. Khokha, and R. , Active allies: hormones, stem cells and the niche in adult mammopoiesis, Trends in Endocrinology & Metabolism, vol.23, issue.6, pp.299-309, 2012.
DOI : 10.1016/j.tem.2012.04.002

M. Kanatsu-shinohara, K. Inoue, S. Takashima, M. Takehashi, N. Ogonuki et al., Reconstitution of Mouse Spermatogonial Stem Cell Niches in Culture, Cell Stem Cell, vol.11, issue.4, pp.567-578, 2012.
DOI : 10.1016/j.stem.2012.06.011

M. Kanatsu-shinohara, N. Ogonuki, K. Inoue, H. Miki, A. Ogura et al., Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells1, Biology of Reproduction, vol.69, issue.2, pp.612-616, 2003.
DOI : 10.1095/biolreprod.103.017012

H. Krishnamurthy, N. Danilovich, C. R. Morales, and M. R. Sairam, Qualitative and Quantitative Decline in Spermatogenesis of the Follicle-Stimulating Hormone Receptor Knockout (FORKO) Mouse1, Biology of Reproduction, vol.62, issue.5, pp.1146-1159, 2000.
DOI : 10.1095/biolreprod62.5.1146

H. Kubota, M. R. Avarbock, and R. L. Brinster, Growth factors essential for selfrenewal and expansion of mouse spermatogonial stem cells, Proc. Natl. Acad. Sci. USA 101, pp.16489-16494, 2004.

G. Loots and I. Ovcharenko, ECRbase: database of evolutionary conserved regions, promoters, and transcription factor binding sites in vertebrate genomes, Bioinformatics, vol.23, issue.1, pp.122-124, 2007.
DOI : 10.1093/bioinformatics/btl546

G. G. Loots and I. Ovcharenko, Mulan: Multiple-Sequence Alignment to Predict Functional Elements in Genomic Sequences, Methods Mol. Biol, vol.395, pp.237-254, 2007.
DOI : 10.1385/1-59745-514-8:237

J. A. Makela, V. Saario, S. Bourguiba-hachemi, M. Nurmio, K. Jahnukainen et al., Hedgehog signalling promotes germ cell survival in the rat testis, Reproduction, vol.142, issue.5, pp.711-721, 2011.
DOI : 10.1530/REP-11-0110

N. Matsushita, Y. Fujita, M. Tanaka, T. Nagatsu, and K. Kiuchi, Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF, Gene, vol.203, issue.2, pp.149-157, 1997.
DOI : 10.1016/S0378-1119(97)00506-4

X. Meng, M. Lindahl, M. E. Hyvonen, M. Parvinen, D. G. De-rooij et al., Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF, Science, vol.287, issue.5457, pp.1489-1493, 2000.
DOI : 10.1126/science.287.5457.1489

M. R. Montminy, K. A. Sevarino, J. A. Wagner, G. Mandel, and R. H. Goodman, Identification of a cyclic-AMP-responsive element within the rat somatostatin gene., Proc. Natl. Acad. Sci. USA, pp.6682-6686, 1986.
DOI : 10.1073/pnas.83.18.6682

L. Ooi and I. C. Wood, Chromatin crosstalk in development and disease: lessons from REST, Nature Reviews Genetics, vol.16, issue.7, pp.544-554, 2007.
DOI : 10.1038/nrg2100

M. Parvinen, Regulation of the Seminiferous Epithelium*, Endocrine Reviews, vol.3, issue.4, pp.404-417, 1982.
DOI : 10.1210/edrv-3-4-404

M. Parvinen, R. Marana, D. M. Robertson, V. Hansson, and M. E. Ritzèn, Functional cycle of Rat Sertoli cells: differential binding and action of Folliclestimulating hormone at various stages of the spermatogenic cycle, Testicular Development, Structure and Function, pp.425-432, 1980.

M. Parvinen and T. Vanha-perttula, Identification and enzyme quantitation of the stages of the seminiferous epithelial wave in the rat, Anat. Rec, vol.174, pp.435-449, 1972.

P. G. Quinn, T. W. Wong, M. A. Magnuson, J. B. Shabb, and D. K. Granner, Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene., Molecular and Cellular Biology, vol.8, issue.8, pp.3467-3475, 1988.
DOI : 10.1128/MCB.8.8.3467

H. Sariola and M. Saarma, Novel functions and signalling pathways for GDNF, Journal of Cell Science, vol.116, issue.19, pp.3855-3862, 2003.
DOI : 10.1242/jcs.00786

T. D. Schmittgen and K. J. Livak, Analyzing real-time PCR data by the comparative CT method, Nature Protocols, vol.2, issue.6, pp.1101-1108, 2008.
DOI : 10.1038/nprot.2008.73

L. Simon, G. C. Ekman, G. Tyagi, R. A. Hess, K. M. Murphy et al., Common and distinct factors regulate expression of mRNA for ETV5 and GDNF, Sertoli cell proteins essential for spermatogonial stem cell maintenance, Experimental Cell Research, vol.313, issue.14, pp.3090-3099, 2007.
DOI : 10.1016/j.yexcr.2007.05.002

Y. Tadokoro, K. Yomogida, H. Ohta, A. Tohda, and Y. Nishimune, Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway, Mechanisms of Development, vol.113, issue.1, pp.29-39, 2002.
DOI : 10.1016/S0925-4773(02)00004-7

M. Tanaka, S. Ito, and K. Kiuchi, Novel alternative promoters of mouse glial cell line-derived neurotrophic factor gene, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1494, issue.1-2, pp.63-74, 2000.
DOI : 10.1016/S0167-4781(00)00218-9

M. Tanaka, S. Ito, and K. Kiuchi, The 5???-untranslated region of the mouse glial cell line-derived neurotrophic factor gene regulates expression at both the transcriptional and translational levels, Molecular Brain Research, vol.91, issue.1-2, pp.81-95, 2001.
DOI : 10.1016/S0169-328X(01)00125-5

M. Tanaka, S. Ito, N. Matsushita, N. Mori, and K. Kiuchi, Promoter analysis and characteristics of the 5???-untranslated region of the mouse glial cell line-derived neurotrophic factor gene, Molecular Brain Research, vol.85, issue.1-2, pp.91-102, 2000.
DOI : 10.1016/S0169-328X(00)00250-3

E. Vicini and M. Conti, Characterization of an intronic promoter of a cyclic adenosine 3 0 ,5 0 -monophosphate (cAMP)-specific phosphodiesterase gene that confers hormone and cAMP inducibility, Mol. Endocrinol, vol.11, pp.839-850, 1997.

W. H. Walker and J. Cheng, FSH and testosterone signaling in Sertoli cells, Reproduction, vol.130, issue.1, pp.15-28, 2005.
DOI : 10.1530/rep.1.00358

W. H. Walker, L. Fucci, and J. F. Habener, Expression of the gene encoding transcription factor cyclic adenosine 3 0 ,5 0 -monophosphate (cAMP) response element-binding protein (CREB): regulation by follicle-stimulating hormoneinduced cAMP signaling in primary rat Sertoli cells, Endocrinology, vol.136, pp.3534-3545, 1995.

W. W. Wasserman, M. Palumbo, W. Thompson, J. W. Fickett, and C. E. Lawrence, Human-mouse genome comparisons to locate regulatory sites, Nature Genetics, vol.266, issue.2, pp.225-228, 2000.
DOI : 10.1038/79965

D. Woodbury, D. G. Schaar, L. Ramakrishnan, and I. B. Black, Novel structure of the human GDNF gene, Brain Research, vol.803, issue.1-2, pp.95-104, 1998.
DOI : 10.1016/S0006-8993(98)00627-1