H. Lashuel, C. Overk, A. Oueslati, and E. Masliah, The many faces of ??-synuclein: from structure and toxicity to therapeutic target, Nature Reviews Neuroscience, vol.418, issue.1, pp.38-48, 2013.
DOI : 10.1038/nrn3406

S. Kim, B. Jeon, C. Heo, P. Im, T. Ahn et al., Alpha-synuclein induces apoptosis by altered expression in human peripheral lymphocyte in Parkinson's disease, FASEB J, vol.18, pp.1615-1617, 2004.

E. Shin, S. Cho, D. Lee, M. Hur, S. Paik et al., Expression Patterns of ??-Synuclein in Human Hematopoietic Cells and in Drosophila at Different Developmental Stages, Molecules and Cells, vol.10, issue.1, pp.65-70, 2000.
DOI : 10.1007/s10059-000-0065-x

L. Kalia, S. Kalia, P. Mclean, A. Lozano, and A. Lang, ??-Synuclein oligomers and clinical implications for Parkinson disease, Annals of Neurology, vol.282, issue.suppl 1, pp.155-169, 2013.
DOI : 10.1002/ana.23746
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608838

K. Vekrellis, M. Xilouri, E. Emmanouilidou, H. Rideout, and L. Stefanis, Pathological roles of ??-synuclein in neurological disorders, The Lancet Neurology, vol.10, issue.11, pp.1015-1025, 2011.
DOI : 10.1016/S1474-4422(11)70213-7

D. Klionsky, Autophagy: from phenomenology to molecular understanding in less than a decade, Nature Reviews Molecular Cell Biology, vol.432, issue.11, pp.931-937, 2007.
DOI : 10.1038/nrm2245

N. Mizushima and D. Klionsky, Protein Turnover Via Autophagy: Implications for Metabolism, Annual Review of Nutrition, vol.27, issue.1, pp.19-40, 2007.
DOI : 10.1146/annurev.nutr.27.061406.093749

S. Engelender, Ubiquitination of ??-synuclein and autophagy in Parkinson's disease, Autophagy, vol.4, issue.3, pp.372-374, 2008.
DOI : 10.4161/auto.5604

M. Martinez-vicente and M. Vila, Alpha-synuclein and protein degradation pathways in Parkinson's disease: A pathological feed-back loop, Experimental Neurology, vol.247, pp.308-313, 2013.
DOI : 10.1016/j.expneurol.2013.03.005

A. Winslow, C. Chen, S. Corrochano, A. Acevedo-arozena, D. Gordon et al., ??-Synuclein impairs macroautophagy: implications for Parkinson???s disease, The Journal of Cell Biology, vol.190, issue.6, pp.1023-1037, 2010.
DOI : 10.1083/jcb.201003122.dv

I. Mcleod, W. Jia, and Y. He, The contribution of autophagy to lymphocyte survival and homeostasis, Immunological Reviews, vol.6, issue.Suppl, pp.195-204, 2012.
DOI : 10.1111/j.1600-065X.2012.01143.x

B. Levine, N. Mizushima, and H. Virgin, Autophagy in immunity and inflammation, Nature, vol.307, issue.7330, pp.323-335, 2011.
DOI : 10.1038/nature09782

M. Pierdominici, M. Vomero, C. Barbati, T. Colasanti, A. Maselli et al., Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus, The FASEB Journal, vol.26, issue.4, pp.1400-1412, 2012.
DOI : 10.1096/fj.11-194175

X. Zhou and H. Zhang, Autophagy in immunity, Autophagy, vol.181, issue.9, pp.1286-1299, 2012.
DOI : 10.1111/j.1600-0625.2009.01039.x

Y. Ma, L. Galluzzi, L. Zitvogel, and G. Kroemer, Autophagy and Cellular Immune Responses, Immunity, vol.39, issue.2, pp.211-227, 2013.
DOI : 10.1016/j.immuni.2013.07.017
URL : http://doi.org/10.1016/j.immuni.2013.07.017

C. Alessandri, C. Barbati, D. Vacirca, P. Piscopo, A. Confaloni et al., T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy, The FASEB Journal, vol.26, issue.11, pp.4722-4732, 2012.
DOI : 10.1096/fj.12-206060

N. Mizushima and T. Yoshimori, How to Interpret LC3 Immunoblotting, Autophagy, vol.3, issue.6, pp.542-545, 2007.
DOI : 10.4161/auto.4600

D. Klionsky, F. Abdalla, H. Abeliovich, R. Abraham, A. Acevedo-arozena et al., Guidelines for the use and interpretation of assays for monitoring autophagy, Autophagy, vol.4, issue.4, pp.445-544, 2012.
DOI : 10.4161/auto.6.4.12244
URL : https://hal.archives-ouvertes.fr/hal-01343085

A. Bellucci, G. Collo, I. Sarnico, L. Battistin, C. Missale et al., receptor activation, Journal of Neurochemistry, vol.17, issue.Suppl. 12, pp.560-577, 2008.
DOI : 10.1111/j.1471-4159.2008.05406.x

Y. Shi, Z. Ding, J. Zhou, B. Hui, G. Shi et al., Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis, Autophagy, vol.7, issue.10, pp.1159-1172, 2011.
DOI : 10.4161/auto.7.10.16818

A. Guidetti, C. Carlo-stella, S. Locatelli, W. Malorni, M. Pierdominici et al., Phase II study of sorafenib in patients with relapsed or refractory lymphoma, British Journal of Haematology, vol.24, issue.1, pp.108-119, 2012.
DOI : 10.1111/j.1365-2141.2012.09139.x

C. Manzoni and P. Lewis, Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies, The FASEB Journal, vol.27, issue.9, pp.3424-3429, 2013.
DOI : 10.1096/fj.12-223842

L. Gerland, L. Genestier, S. Peyrol, M. Michallet, S. Hayette et al., Autolysosomes accumulate during in vitro CD8+ T-lymphocyte aging and may participate in induced death sensitization of senescent cells, Experimental Gerontology, vol.39, issue.5, pp.789-800, 2004.
DOI : 10.1016/j.exger.2004.01.013

K. Phadwal, J. Alegre-abarrategui, A. Watson, L. Pike, S. Anbalagan et al., A novel method for autophagy detection in primary cells, Autophagy, vol.66, issue.4, pp.677-689, 2012.
DOI : 10.1002/path.2094

M. He and Y. He, A role for c-FLIPL in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes, Cell Death and Differentiation, vol.30, issue.2, pp.188-197, 2013.
DOI : 10.1038/cdd.2012.148

J. Song, J. Lu, L. Liu, L. Chen, S. Durairajan et al., HMGB1 is involved in autophagy inhibition caused by SNCA/??-synuclein overexpression, Autophagy, vol.18, issue.1, pp.144-154, 2013.
DOI : 10.1074/jbc.M208001200

J. Huang, K. Liu, Y. Yu, M. Xie, R. Kang et al., Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma, Autophagy, vol.8, issue.2, pp.275-277, 2012.
DOI : 10.4161/auto.8.2.18940

M. Djavaheri-mergny, M. Maiuri, and G. Kroemer, Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1, Oncogene, vol.11, issue.12, pp.1717-1719, 2010.
DOI : 10.1038/ncb1482

A. Eisenberg-lerner, S. Bialik, H. Simon, and A. Kimchi, Life and death partners: apoptosis, autophagy and the cross-talk between them, Cell Death and Differentiation, vol.4, issue.7, pp.966-975, 2009.
DOI : 10.1038/ncb1736

G. Nagy, A. Koncz, and A. Perl, T- and B-Cell Abnormalities in Systemic Lupus Erythematosus, Critical Reviews in Immunology, vol.25, issue.2, pp.123-140, 2005.
DOI : 10.1615/CritRevImmunol.v25.i2.30

D. Fernandez, E. Bonilla, N. Mirza, B. Niland, and P. A. , Rapamycin reduces disease activity and normalizes T cell activation???induced calcium fluxing in patients with systemic lupus erythematosus, Arthritis & Rheumatism, vol.7, issue.9, pp.2983-2988, 2006.
DOI : 10.1002/art.22085

L. Leslie and A. Younes, Targeting oncogenic and epigenetic survival pathways in lymphoma, Leukemia & Lymphoma, vol.8, issue.1, pp.2365-2376, 2013.
DOI : 10.1073/pnas.1108190108

P. Singh, V. Kotia, D. Ghosh, G. Mohite, A. Kumar et al., Curcumin Modulates ??-Synuclein Aggregation and Toxicity, ACS Chemical Neuroscience, vol.4, issue.3, pp.393-407, 2013.
DOI : 10.1021/cn3001203
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605819

M. Hochberg, Updating the American college of rheumatology revised criteria for the classification of systemic lupus erythematosus, Arthritis & Rheumatism, vol.74, issue.9, p.1725, 1997.
DOI : 10.1002/art.1780400928

K. Habig, M. Walter, H. Stappert, O. Riess, and M. Bonin, Microarray expression analysis of human dopaminergic neuroblastoma cells after RNA interference of SNCA ??? A key player in the pathogenesis of Parkinson's disease, Brain Research, vol.1256, pp.19-33, 2009.
DOI : 10.1016/j.brainres.2008.12.020

T. Colasanti, A. Maselli, F. Conti, M. Sanchez, C. Alessandri et al., Autoantibodies to estrogen receptor ?? interfere with T lymphocyte homeostasis and are associated with disease activity in systemic lupus erythematosus, Arthritis & Rheumatism, vol.15, issue.3, pp.778-787, 2012.
DOI : 10.1002/art.33400

B. Lee and T. Kamitani, Improved Immunodetection of Endogenous ??-Synuclein, PLoS ONE, vol.85, issue.8, p.23939, 2011.
DOI : 10.1371/journal.pone.0023939.g010

F. Gros, J. Arnold, N. Page, M. Decossas, A. Korganow et al., Macroautophagy is deregulated in murine and human lupus T lymphocytes, Autophagy, vol.4, issue.7, pp.1113-1123, 2012.
DOI : 10.4049/jimmunol.1000576
URL : https://hal.archives-ouvertes.fr/hal-00715328