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Journal articles
Prenatal maternal stress alters placental serotonin system in a foetal sex dependent manner
Abstract : Prenatal maternal stress (PNMS) is associated with children neurodevelopmental disorders. Serotonin is a crucial hormone, produced and transported by the placenta, for fetal brain development. Stress is known to affect serotonin reuptake by the serotonin transporter (SERT). Placental type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) protects the fetus by converting cortisol into inactive cortisone. Excess cortisol such as in PNMS is linked with serotonin-related pathological conditions (e.g. preeclampsia, autism), but the effect of PNMS on the placental serotonin systemhas never been studied.
https://hal-riip.archives-ouvertes.fr/pasteur-01351712
Contributor : Michel Courcelles Connect in order to contact the contributor
Submitted on : Thursday, August 4, 2016 - 3:46:58 PM
Last modification on : Thursday, June 18, 2020 - 12:58:24 PM
Contributor : Michel Courcelles Connect in order to contact the contributor
Submitted on : Thursday, August 4, 2016 - 3:46:58 PM
Last modification on : Thursday, June 18, 2020 - 12:58:24 PM