Melatonin regulates autophagy and inflammation in human trophoblastic cells

Lucas Sagrillo Fagundes 1 Eugênia Maria 1 Assunção Salustiano 1 Philippe Wong Yen 1 Cathy Vaillancourt 1
1 INRS-IAF - Institut Armand Frappier
Abstract : Melatonin is produced by and protects villous trophoblasts against hypoxia/reoxygenation (H/R)-induced oxidative stress and apoptosis. However, melatonin’s anti-inflammatory activity and induction of autophagy in villous trophoblasts under H/R have never been investigated.
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Submitted on : Friday, August 5, 2016 - 3:53:10 PM
Last modification on : Monday, October 8, 2018 - 5:44:05 PM

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Lucas Sagrillo Fagundes, Eugênia Maria, Assunção Salustiano, Philippe Wong Yen, Cathy Vaillancourt. Melatonin regulates autophagy and inflammation in human trophoblastic cells. Placenta, Elsevier, 2015, 36 (9), pp.A51-A52. ⟨10.1016/j.placenta.2015.07.342⟩. ⟨pasteur-01352136⟩

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