Pseudotumoral cutaneous aspergillosis in chronic granulomatous disease, report of a pediatric case. - Archive ouverte HAL Access content directly
Journal Articles American Journal of Dermatopathology Year : 2012

Pseudotumoral cutaneous aspergillosis in chronic granulomatous disease, report of a pediatric case.

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Abstract

Invasive aspergillosis is a life-threatening condition in patients with chronic granulomatous disease (CGD). Skin invasion by Aspergillus occurs most commonly by contiguity to a neighboring cavity. We describe an unusual case of invasive cutaneous aspergillosis presented as a large burgeoning tumor in a 4-year-old girl with CGD who underwent surgical treatment for bifocal osteomyelitis of the left leg. The skin invasion occurred 4 months after a "successful" treatment of invasive pulmonary aspergillosis. Atypical presentation and diagnostic difficulties are discussed. Invasive cutaneous aspergillosis may be polymorphic. The diagnosis should be considered early in the etiological investigation of any suspicious skin lesions in CGD even in uncommon aspects such as burgeoning tumors.
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Dates and versions

pasteur-01375149 , version 1 (02-10-2016)

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Monia Khemiri, Nadia El Fekih, Aida Borgi, Monia Kharfi, Samir Boubaker, et al.. Pseudotumoral cutaneous aspergillosis in chronic granulomatous disease, report of a pediatric case.. American Journal of Dermatopathology, 2012, 34 (7), pp.749-52. ⟨10.1097/DAD.0b013e3182562451⟩. ⟨pasteur-01375149⟩

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