A Novel Picornavirus Associated with Gastroenteritis

Abstract : A novel picornavirus genome was sequenced, showing 42.6%, 35.2%, and 44.6% of deduced amino acid identities corresponding to the P1, P2, and P3 regions, respectively, of the Aichi virus. Divergent strains of this new virus, which we named salivirus, were detected in 18 stool samples from Nigeria, Tunisia, Nepal, and the United States. A statistical association was seen between virus shedding and unexplained cases of gastroenteritis in Nepal (P = 0.0056). Viruses with approximately 90% nucleotide similarity, named klassevirus, were also recently reported in three cases of unexplained diarrhea from the United States and Australia and in sewage from Spain, reflecting a global distribution and supporting a pathogenic role for this new group of picornaviruses.
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Journal of Virology, American Society for Microbiology, 2009, 83 (22), pp.12002-12006. 〈10.1128/JVI.01241-09〉
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Linlin Li, Joseph Victoria, Amit Kapoor, Olga Blinkova, Chunlin Wang, et al.. A Novel Picornavirus Associated with Gastroenteritis. Journal of Virology, American Society for Microbiology, 2009, 83 (22), pp.12002-12006. 〈10.1128/JVI.01241-09〉. 〈pasteur-01375331〉

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