Leukemia in Patients with Klinefelter Syndrome: A Report of Two Cases.

B Bchir 1 B Ayed 2 B Neji 1 B Kilani 2 A Kefi 1 A Zarrouk 1 B Guermani 2 B Hentati 2 B Amouri 2 B Meddeb 1
1 Department of Hematology
2 Institut Pasteur de Tunis
Abstract : Klinefelter syndrome (KS) is a chromosome abnormality characterized by a 47, XXY karyotype associated with hypogonadism and infertility. We present two cases of leukemia in patients with KS. The first patient presented with acute promyelocytic leukemia. He relapsed after the end of treatment. The second patient was diagnosed with chronic myeloid leukemia. Treatment with imatinib failed and the patient presented with myeloid blast crisis.
Keywords : Chronic myelogenous leukemia Acute promyelocytic leukemia Karyotype Klinefelter syndrome
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Article dans une revue
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2016, pp.66-8. 〈10.1007/s12288-015-0590-6〉
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Dernière modification le : lundi 8 octobre 2018 - 17:44:08
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B Bchir, B Ayed, B Neji, B Kilani, A Kefi, et al.. Leukemia in Patients with Klinefelter Syndrome: A Report of Two Cases.. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2016, pp.66-8. 〈10.1007/s12288-015-0590-6〉. 〈pasteur-01405779〉

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