Leukemia in Patients with Klinefelter Syndrome: A Report of Two Cases.

B Bchir; B Ayed; B Neji; B Kilani; A Kefi; A Zarrouk; B Guermani; B Hentati; B Amouri; B Meddeb

doi:10.1007/s12288-015-0590-6

Leukemia in Patients with Klinefelter Syndrome: A Report of Two Cases.

B Bchir ¹ B Ayed ² B Neji ¹ B Kilani ² A Kefi ¹ A Zarrouk ¹ B Guermani ² B Hentati ² B Amouri ² B Meddeb ¹

Abstract : Klinefelter syndrome (KS) is a chromosome abnormality characterized by a 47, XXY karyotype associated with hypogonadism and infertility. We present two cases of leukemia in patients with KS. The first patient presented with acute promyelocytic leukemia. He relapsed after the end of treatment. The second patient was diagnosed with chronic myeloid leukemia. Treatment with imatinib failed and the patient presented with myeloid blast crisis.

Keywords : Chronic myelogenous leukemia Acute promyelocytic leukemia Karyotype Klinefelter syndrome

Type de document :

Article dans une revue

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2016, pp.66-8. 〈10.1007/s12288-015-0590-6〉

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Dernière modification le : lundi 5 février 2018 - 15:22:12
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