Service interruption on Monday 11 July from 12:30 to 13:00: all the sites of the CCSD (HAL, EpiSciences, SciencesConf, AureHAL) will be inaccessible (network hardware connection).
Skip to Main content Skip to Navigation
Journal articles

Current approaches and challenges for chemical characterization of inhibitory effect against cancer cell line isolated from Gokshur extract.

Abstract : In the present study, the potential effect anti tumor and the chemical composition of different fractions of Gokshur was evaluated. Commonly known as puncture vine, it has been used for a long time in both the Indian and traditional Chinese medicine. It is popularly used as a remedy for fertility disorder in Ayurveda. Samples were collected during June-September 2014 in the Cap Bon (north east of the northern Tunisia). Different organs were separated and extracted by sequential process to compare and investigate their potential anti-tumor effect. For the first time, we report the antiproliferatif effect of leaves n-butannolic fraction against cancer cell lines. The better anti-tumor fraction (94.76±1.52%) has been detected and performed by RP-HPLC has shown a great peak area (5578.21Mau). Novel designed natural derivatives from Gokshur, a cyclotrisiloxane, major compound identified by GC-MS.
Document type :
Journal articles
Complete list of metadata

https://hal-riip.archives-ouvertes.fr/pasteur-01463317
Contributor : Institut Pasteur Tunis Connect in order to contact the contributor
Submitted on : Thursday, February 9, 2017 - 2:53:57 PM
Last modification on : Monday, July 4, 2022 - 8:51:42 AM

Identifiers

Citation

Salwa Bouabdallah, Rabiaa-M Sghaier, Sawssen Selmi, Daycem Khlifi, Dhafer Laouini, et al.. Current approaches and challenges for chemical characterization of inhibitory effect against cancer cell line isolated from Gokshur extract.. Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, Elsevier, 2016, pp.279-85. ⟨10.1016/j.jchromb.2015.11.023⟩. ⟨pasteur-01463317⟩

Share

Metrics

Record views

97