A. Corfield, Mucins: A biologically relevant glycan barrier in mucosal protection, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1850, issue.1, pp.236-252, 2015.
DOI : 10.1016/j.bbagen.2014.05.003

D. Kufe, Mucins in cancer: function, prognosis and therapy, Nature Reviews Cancer, vol.34, issue.12, pp.874-885, 2009.
DOI : 10.1615/CritRevImmunol.v27.i5.40

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951677/pdf

S. Rachagani, M. Torres, N. Moniaux, and S. Batra, Current status of mucins in the diagnosis and therapy of cancer, BioFactors, vol.37, issue.Pt 1, pp.509-527, 2009.
DOI : 10.1093/oxfordjournals.jbchem.a022746

N. Jonckheere, N. Skrypek, and I. Van-seuningen, Mucins and tumor resistance to chemotherapeutic drugs, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1846, issue.1, pp.142-151, 2014.
DOI : 10.1016/j.bbcan.2014.04.008

R. Beatson, J. Taylor-papadimitriou, and J. Burchell, MUC1 immunotherapy, MUC1 immunotherapy, pp.305-327, 2010.
DOI : 10.1158/0008-5472.CAN-07-2249

T. Kimura and O. Finn, MUC1 immunotherapy is here to stay, Expert Opinion on Biological Therapy, vol.25, issue.1, pp.35-49, 2013.
DOI : 10.1097/CJI.0b013e318243f213

I. Häuselmann and L. Borsig, Altered tumor-cell glycosylation promotes metastasis, Front Oncol, vol.4, pp.28-2014

S. Kaur, S. Kumar, N. Momi, A. Sasson, and S. Batra, Mucins in pancreatic cancer and its microenvironment, Nature Reviews Gastroenterology & Hepatology, vol.27, issue.10, pp.607-620, 2013.
DOI : 10.1016/S0968-0004(01)02049-7

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934431/pdf

. Workman-hc, C. Sweeney, K. Carraway, and . Iii, The Membrane Mucin Muc4 Inhibits Apoptosis Induced by Multiple Insults via ErbB2-Dependent and ErbB2-Independent Mechanisms, Cancer Research, vol.69, issue.7, pp.2845-2852, 2009.
DOI : 10.1158/0008-5472.CAN-08-2089

. Valque-h, V. Gouyer, F. Gottrand, and J. Desseyn, MUC5B Leads to Aggressive Behavior of Breast Cancer MCF7 Cells, PLoS ONE, vol.7, issue.10, p.46699, 2012.
DOI : 10.1371/journal.pone.0046699.t001

. Hoshi-h, T. Sawada, M. Uchida, . Saito-h, . Iijima-h et al., Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer, Int J Oncol, vol.38, pp.619-627, 2011.

S. Yamazoe, . Tanaka-h, T. Sawada, R. Amano, N. Yamada et al., RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells, Journal of Experimental & Clinical Cancer Research, vol.29, issue.1, p.53, 2010.
DOI : 10.1186/1756-9966-29-53

S. Chauhan, M. Ebeling, D. Maher, M. Koch, A. Watanabe et al., MUC13 Mucin Augments Pancreatic Tumorigenesis, Molecular Cancer Therapeutics, vol.11, issue.1, pp.13-24, 2012.
DOI : 10.1158/1535-7163.MCT-11-0598

URL : http://mct.aacrjournals.org/content/molcanther/11/1/24.full.pdf

D. Maher, B. Gupta, S. Nagata, M. Jaggi, and S. Chauhan, Mucin 13: Structure, Function, and Potential Roles in Cancer Pathogenesis, Molecular Cancer Research, vol.9, issue.5, pp.531-537, 2011.
DOI : 10.1158/1541-7786.MCR-10-0443

URL : http://mcr.aacrjournals.org/content/molcanres/9/5/531.full.pdf

I. Lakshmanan, M. Ponnusamy, S. Das, S. Chakraborty, D. Mukhopadhyay et al., MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells, Oncogene, vol.426, issue.7, pp.805-817, 2012.
DOI : 10.1042/BJ20090615

T. Tinder, D. Subramani, G. Basu, J. Bradley, J. Schettini et al., MUC1 Enhances Tumor Progression and Contributes Toward Immunosuppression in a Mouse Model of Spontaneous Pancreatic Adenocarcinoma, The Journal of Immunology, vol.181, issue.5, pp.1-3116, 2008.
DOI : 10.4049/jimmunol.181.5.3116

E. Gottfried, M. Kreutz, and A. Mackensen, Tumor-induced modulation of dendritic cell function, Cytokine & Growth Factor Reviews, vol.19, issue.1, pp.65-77, 2008.
DOI : 10.1016/j.cytogfr.2007.10.008

R. Steinman, Decisions About Dendritic Cells: Past, Present, and Future, Annual Review of Immunology, vol.30, issue.1, pp.1-22, 2012.
DOI : 10.1146/annurev-immunol-100311-102839

URL : http://www.annualreviews.org/doi/pdf/10.1146/annurev-immunol-100311-102839

C. Carlos, D. Howard, O. Oppenheim, J. Finn, and O. , Human Tumor Antigen MUC1 Is Chemotactic for Immature Dendritic Cells and Elicits Maturation but Does Not Promote Th1 Type Immunity, The Journal of Immunology, vol.175, issue.3, pp.1628-1635, 2005.
DOI : 10.4049/jimmunol.175.3.1628

URL : http://www.jimmunol.org/content/jimmunol/175/3/1628.full.pdf

P. Monti, B. Leone, A. Zerbi, G. Balzano, S. Cainarca et al., Tumorderived MUC1 mucins interact with differentiating monocytes and induce IL-10highIL-12low regulatory dendritic cell The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells, J Immunol J Immunol, vol.172, issue.165, pp.7341-7349, 2000.

A. Rughetti, I. Pellicciotta, M. Biffoni, M. Bäckström, T. Link et al., Recombinant Tumor-Associated MUC1 Glycoprotein Impairs the Differentiation and Function of Dendritic Cells, The Journal of Immunology, vol.174, issue.12, pp.7764-7772, 2005.
DOI : 10.4049/jimmunol.174.12.7764

T. Freire, R. Lo-man, S. Bay, and C. Leclerc, Tn Glycosylation of the MUC6 Protein Modulates Its Immunogenicity and Promotes the Induction of Th17-biased T Cell Responses, Journal of Biological Chemistry, vol.178, issue.10, pp.7797-7811, 2011.
DOI : 10.1182/blood-2008-05-158469

A. Ishida, M. Ohta, M. Toda, T. Murata, T. Usui et al., Mucin-induced apoptosis of monocyte-derived dendritic cells during maturation, PROTEOMICS, vol.14, issue.16, pp.3342-3349, 2008.
DOI : 10.4049/jimmunol.172.12.7341

M. Andrianifahanana, N. Moniaux, and S. Batra, Regulation of mucin expression: Mechanistic aspects and implications for cancer and inflammatory diseases, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1765, issue.2, pp.189-222, 2006.
DOI : 10.1016/j.bbcan.2006.01.002

M. Roy, A. Livraghi-butrico, A. Fletcher, M. Mcelwee, S. Evans et al., Muc5b is required for airway defence, Nature, vol.31, issue.7483, pp.412-416, 2014.
DOI : 10.1165/rcmb.2004-0060OC

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001806/pdf

C. Sóñora, D. Mazal, N. Berois, M. Buisine, L. Ubillos et al., Immunohistochemical Analysis of MUC5B Apomucin Expression in Breast Cancer and Non-malignant Breast Tissues, Journal of Histochemistry & Cytochemistry, vol.69, issue.3, pp.289-299, 2006.
DOI : 10.1002/(SICI)1097-0215(19961220)69:6<457::AID-IJC7>3.0.CO;2-3

M. Buisine, L. Devisme, P. Degand, M. Dieu, B. Gosselin et al., Developmental Mucin Gene Expression in the Gastroduodenal Tract and Accessory Digestive Glands. II. Duodenum and Liver, Gallbladder, and Pancreas, Journal of Histochemistry & Cytochemistry, vol.27, issue.12, pp.1667-1676, 2000.
DOI : 10.1002/hep.1840080619

M. Walsh, M. Clendenning, E. Williamson, S. Pearson, R. Walters et al., Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype, Modern Pathology, vol.13, issue.12, pp.1642-1656, 2013.
DOI : 10.1053/j.gastro.2006.08.038

N. Berois, M. Varangot, C. Sóñora, L. Zarantonelli, C. Pressa et al., Detection of bone marrow-disseminated breast cancer cells using an RT-PCR assay of MUC5B mRNA, International Journal of Cancer, vol.251, issue.4, pp.550-555, 2003.
DOI : 10.1006/bbrc.1998.9469

I. Tiscornia, V. Sánchez-martins, A. Hernández, and M. Bollati-fogolín, Human monocyte-derived dendritic cells from leukoreduction system chambers after plateletpheresis are functional in an in vitro co-culture assay with intestinal epithelial cells, Journal of Immunological Methods, vol.384, issue.1-2, pp.164-170, 2012.
DOI : 10.1016/j.jim.2012.07.005

URL : https://hal.archives-ouvertes.fr/pasteur-00839679

L. Hp and C. Chao, Cancer cells acquire resistance to anticancer drugs: An update, Biomed J, vol.35, pp.464-472, 2012.

S. Anguille, E. Smits, E. Lion, V. Van-tendeloo, and B. Zn, Clinical use of dendritic cells for cancer therapy, The Lancet Oncology, vol.15, issue.7, pp.257-267, 2014.
DOI : 10.1016/S1470-2045(13)70585-0

J. Hegmans and J. Aerts, Immunomodulation in cancer, Current Opinion in Pharmacology, vol.17, pp.17-21, 2014.
DOI : 10.1016/j.coph.2014.06.007

T. Pandit, W. Kennette, L. Mackenzie, G. Zhang, W. Al-katib et al., Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment, Int J Oncol, vol.35, pp.297-308, 2009.

M. Mimeault, S. Johansson, S. Senapati, N. Momi, S. Chakraborty et al., MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies, Cancer Letters, vol.295, issue.1, pp.69-84, 2010.
DOI : 10.1016/j.canlet.2010.02.015

A. Kalra and R. Campbell, Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain, British Journal of Cancer, vol.7, issue.7, pp.910-918, 2007.
DOI : 10.1007/s005340200037

J. Ren, A. N. Chen, D. Li, Y. , Y. Wh et al., Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents, Cancer Cell, vol.5, issue.2, pp.163-175, 2004.
DOI : 10.1016/S1535-6108(04)00020-0

URL : https://doi.org/10.1016/s1535-6108(04)00020-0

M. Siragusa, M. Zerilli, F. Iovino, M. Francipane, Y. Lombardo et al., MUC1 Oncoprotein Promotes Refractoriness to Chemotherapy in Thyroid Cancer Cells, Cancer Research, vol.67, issue.11, pp.5522-5530, 2007.
DOI : 10.1158/0008-5472.CAN-06-4197

URL : http://cancerres.aacrjournals.org/content/canres/67/11/5522.full.pdf

N. Skrypek, B. Duchêne, M. Hebbar, E. Leteurtre, I. Van-seuningen et al., The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family, Oncogene, vol.377, issue.13, pp.1714-1723, 2013.
DOI : 10.1042/bj20031132

URL : https://hal.archives-ouvertes.fr/inserm-00807837

A. Kalra and R. Campbell, Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours, European Journal of Cancer, vol.45, issue.1, pp.164-173, 2009.
DOI : 10.1016/j.ejca.2008.10.008

S. Nath, K. Daneshvar, L. Roy, P. Grover, A. Kidiyoor et al., MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes, Oncogenesis, vol.181, issue.6, pp.1-51, 2013.
DOI : 10.4049/jimmunol.181.5.3116

M. Patankar, Y. Jing, J. Morrison, J. Belisle, F. Lattanzio et al., Potent suppression of natural killer cell response mediated by the ovarian tumor marker CA125, Gynecologic Oncology, vol.99, issue.3, pp.704-713, 2005.
DOI : 10.1016/j.ygyno.2005.07.030

J. Belisle, S. Jennifer, G. Petrie, S. Kapur, A. André et al., Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes, Molecular Cancer, vol.9, issue.1, p.118, 2010.
DOI : 10.1186/1476-4598-9-118

T. Freire and E. Osinaga, The sweet side of tumor immunotherapy, Immunotherapy, vol.9, issue.7, pp.719-734, 2012.
DOI : 10.1007/s10522-008-9150-x

URL : https://hal.archives-ouvertes.fr/pasteur-00844603