Alginate based nanocomposite for microencapsulation of probiotic: Effect of cellulose nanocrystal (CNC) and lecithin.

Tanzina Huq (1) , Carole Fraschini (2) , Avik Khan (3) , Bernard Riedl (4) , Jean Bouchard (2) , Monique Lacroix (1)

1 INRS-IAF - Institut Armand Frappier
2 FPInnovations
3 UNB - University of New Brunswick
4 ULaval - Université Laval [Québec]

Probiotic (Lactobacillus rhamnosus ATCC 9595) was encapsulated in alginate-CNC-lecithin microbeads to produce nutraceutical microcapsules. Addition of CNC and lecithin in alginate microbeads (ACL-1) improved the viability of L. rhamnosus during gastric passage and storage. The compression strength of the freeze-dried ACL-1 microbeads improved 40% compared to alginate microbeads alone. Swelling studies revealed that addition of CNC and lecithin in alginate microbeads decreased (around 47%) the gastric fluid absorption but increased the dissolution time by 20min compared to alginate microbeads (A-0). During transition through the gastric passage, the viability of L. rhamnosus in dried ACL-1 microbeads was increased 37% as compared to A-0 based beads. At 25 and 4°C storage conditions, the viability of L. rhamnosus encapsulated in ACL-1 microbeads decreased by 1.23 and 1.08 log respectively, whereas the encapsulation with A-0 microbeads exhibited a 3.17 and 1.93 log reduction respectively.

Mots clés: Alginate; Cellulose nanocrystals; Freeze drying; Microcapsule; Probiotic

Domaines: Sciences du Vivant [q-bio]

Tanzina Huq, Carole Fraschini, Avik Khan, Bernard Riedl, Jean Bouchard, et al.. Alginate based nanocomposite for microencapsulation of probiotic: Effect of cellulose nanocrystal (CNC) and lecithin.. Carbohydrate Polymers, 2017, 168, pp.61-69. ⟨10.1016/j.carbpol.2017.03.032⟩. ⟨pasteur-01534655⟩