Early Guillain–Barré Syndrome associated with acute dengue fever

O. Simon (1) , S. Billot (1) , D. Guyon (1) , M. Daures (2) , E. Descloux (3) , A.C. Gourinat (4) , N. Molko (5, 1) , M. Dupont-Rouzeyrol (6)

1 Centre hospitalier territorial Gaston-Bourret [Nouméa]
2 New Caledonia Health Department
3 Department of Internal Medicine and Infectious Diseases
4 Institut Pasteur de Nouvelle-Calédonie
5 SHFJ - Service Hospitalier Frédéric Joliot
6 URE-DA - Dengue et Arbovirose

Various forms of neurological manifestations are reported in dengue fever. We describe here three cases of concomitant Guillain-Barré syndrome and dengue virus (DENV) infection during the largest DENV-1 outbreak in New Caledonia. Research of viral RNA was positive in both blood and CSF samples. All patients were treated with intravenous polyvalent immunoglobulins and recovered without sequelae within one week.

Keywords: Acute; Dengue; Guillain–Barré Syndrome; Infectious disease; Neurology

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Human health and pathology; Emerging diseases; Life Sciences [q-bio]; Neurons and Cognition [q-bio.NC]; Neurobiology

O. Simon, S. Billot, D. Guyon, M. Daures, E. Descloux, et al.. Early Guillain–Barré Syndrome associated with acute dengue fever. Journal of Clinical Virology, 2016, 77, pp.29 - 31. ⟨10.1016/j.jcv.2016.01.016⟩. ⟨pasteur-01634325⟩