Vertical Transmission of Dengue Virus in the Peripartum Period and Viral Kinetics in Newborns and Breast Milk: New Data

Lucille Arragain (1) , Myrielle Dupont-Rouzeyrol (2) , Olivia O'Connor (2) , Nathalie Sigur (1) , Jean-Paul Grangeon (3) , Emilie Huguon (1) , Clothilde Dechanet (1) , Cecile Cazorla (1) , Ann-Claire Gourinat (4) , Elodie Descloux (1)

1 Centre hospitalier territorial Gaston-Bourret [Nouméa]
2 URE-DA - Dengue et Arbovirose
3 Direction des affaires sanitaires et sociales de Nouvelle-Calédonie
4 Institut Pasteur de Nouvelle-Calédonie

We investigated 10 mother-newborn pairs and found a 90% rate of dengue virus (DENV) transmission during the perinatal period. Here, we describe DENV kinetics in the sera of newborns before the onset of disease. Of the breast-milk samples analyzed, 75% tested positive for DENV.

Keywords: breast milk; dengue; kinetics; transmission; vertical

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Microbiology and Parasitology; Virology

Lucille Arragain, Myrielle Dupont-Rouzeyrol, Olivia O'Connor, Nathalie Sigur, Jean-Paul Grangeon, et al.. Vertical Transmission of Dengue Virus in the Peripartum Period and Viral Kinetics in Newborns and Breast Milk: New Data. Journal of the Pediatric Infectious Diseases Society, 2016, ⟨10.1093/jpids/piw058⟩. ⟨pasteur-01634331⟩