Lactase persistence in Tunisia as a result of admixture with other Mediterranean populations

Abstract : Background: The ability to digest lactose after weaning, namely, lactase persistence (LP), is encoded by polymorphisms in the MCM6 gene and varies widely in frequency among different human populations. Although, evolution of LP-related genetic variants was investigated in many groups of Sub-Saharan African, Middle Eastern, and European ancestry, only few studies have focused on populations from North Africa and no data are especially available from the Tunisian one. For this reason, there is an urgent need to investigate the frequency patterns at these loci in Tunisia since this adaptive trait is implicated in health.
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Soumis le : vendredi 17 novembre 2017 - 10:38:21
Dernière modification le : mercredi 29 novembre 2017 - 01:15:55

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Yosra Halima, Rym Kefi, Marco Sazzini, Cristina Giuliani, Sara De Fanti, et al.. Lactase persistence in Tunisia as a result of admixture with other Mediterranean populations. Genes and Nutrition, BioMed Central, 2017, 12 (1), pp.20. 〈10.1186/s12263-017-0573-3〉. 〈pasteur-01636913〉

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