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Évaluation de la performance du test de diagnostic rapide du paludisme OnSite à Miandrivazo, Madagascar

Abstract : The performance of the malaria rapid diagnostic test OnSite — for detecting pan specific pLDH and Plasmo-dium falciparum specific HRP2 — was assessed during the malaria transmission peak period in Miandrivazo, in the southwestern part of Madagascar from April 20 to May 6, 2010. At the laboratory, the quality control OnSite Malaria Rapid Test according to the WHO/TDR/FIND method demonstrated that the test had good sensitivity. Of the 218 OnSite tests performed at the Miandrivazo Primary Health Center on patients with fever or a recent history of fever, four (1.8%, 95% CI: 0.6–4.9%) were invalid. Ninety four (43,1%) cases of malaria were confirmed by microscopy, of which 90 were P. falciparum malaria and 4 Plasmo-dium vivax malaria. With a Cohen's kappa coefficient of 0.94, the agreement between microscopy and OnSite is excellent. Compared with the rapid test CareStart™ commonly used within the public health structures in Madagas-car, the sensitivity and specificity of the OnSite test were 97.9% and 96.8%.
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E. Ravaoarisoa, T. Andriamindranoro, R. Raherinjafy, M. Jahevitra, S. Razanatsiorimalala, et al.. Évaluation de la performance du test de diagnostic rapide du paludisme OnSite à Miandrivazo, Madagascar. Bulletin de la Société de pathologie exotique , Masson, 2017, 110 (4), pp.254 - 259. ⟨10.1007/s13149-017-0568-8⟩. ⟨pasteur-01670498⟩



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