Service interruption on Monday 11 July from 12:30 to 13:00: all the sites of the CCSD (HAL, Epiciences, SciencesConf, AureHAL) will be inaccessible (network hardware connection).
Skip to Main content Skip to Navigation
Journal articles

Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance

Abstract : Together with influenza, the non-influenza RNA respiratory viruses (NIRVs), which include respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human metapneumovirus, represent a considerable global health burden, as recognised by WHO's Battle against Respiratory Viruses initiative. By contrast with influenza viruses, little is known about the contemporaneous global diversity of these viruses, and the relevance of such for development of pharmaceutical interventions. Although far less advanced than for influenza, antiviral drugs and vaccines are in different stages of development for several of these viruses, but no interventions have been licensed. This scarcity of global genetic data represents a substantial knowledge gap and impediment to the eventual licensing of new antiviral drugs and vaccines for NIRVs. Enhanced genetic surveillance will assist and boost research and development into new antiviral drugs and vaccines for these viruses. Additionally, understanding the global diversity of respiratory viruses is also part of emerging disease preparedness, because non-human coronaviruses and paramyxoviruses have been listed as priority concerns in a recent WHO research and development blueprint initiative for emerging infectious diseases. In this Personal View, we explain further the rationale for expanding the genetic database of NIRVs and emphasise the need for greater investment in this area of research.
Complete list of metadata

Cited literature [62 references]  Display  Hide  Download
Contributor : Jean-Michel Heraud Connect in order to contact the contributor
Submitted on : Wednesday, February 28, 2018 - 3:00:47 PM
Last modification on : Tuesday, June 15, 2021 - 4:46:01 PM
Long-term archiving on: : Monday, May 28, 2018 - 2:42:00 PM


Files produced by the author(s)



Julian W Tang, Tommy T Lam, Hassan Zaraket, Ian Lipkin, Steven J Drews, et al.. Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance. The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2017, 17 (10), pp.e320 - e326. ⟨10.1016/S1473-3099(17)30238-4⟩. ⟨pasteur-01675136⟩



Record views


Files downloads