Respiratory syncytial virus infection in the elderly, European Journal of Clinical Microbiology & Infectious Diseases, vol.125, issue.10, pp.777-81, 1996. ,
DOI : 10.1093/infdis/165.6.987
The ???Common Cold??? in Frail Older Persons: Impact of Rhinovirus and Coronavirus in a Senior Daycare Center, Journal of the American Geriatrics Society, vol.44, issue.6, pp.706-717, 1997. ,
DOI : 10.1111/j.1532-5415.1996.tb01859.x
Rhinovirus and Coronavirus Infection???Associated Hospitalizations among Older Adults, The Journal of Infectious Diseases, vol.185, issue.9, pp.1338-1379, 2002. ,
DOI : 10.1086/339881
URL : https://academic.oup.com/jid/article-pdf/185/9/1338/18006519/185-9-1338.pdf
Respiratory Syncytial Virus Pneumonia among the Elderly: An Assessment of Disease Burden, The Journal of Infectious Diseases, vol.179, issue.1, pp.25-30, 1999. ,
DOI : 10.1086/314567
Human Coronavirus and Acute Respiratory Illness in Older Adults with Chronic Obstructive Pulmonary Disease, The Journal of Infectious Diseases, vol.199, issue.6, pp.847-57, 2009. ,
DOI : 10.1086/597122
Respiratory syncytial virus and parainfluenza virus infections in the immunocompromised host, Semin Respir Infect, vol.10, pp.224-255, 1995. ,
A multi-drug regimen for respiratory syncytial virus and parainfluenza virus infections in adult lung and heart-lung transplant recipients, Transplant Infectious Disease, vol.12, issue.1, pp.38-44, 2010. ,
DOI : 10.1111/j.1399-3062.2009.00453.x
Human metapneumovirus pneumonia in patients with hematological malignancies, Journal of Clinical Virology, vol.61, issue.4, pp.593-599, 2014. ,
DOI : 10.1016/j.jcv.2014.08.019
Medical Burden of Respiratory Syncytial Virus and Parainfluenza Virus Type 3 Infection Among US Children: Implications for Design of Vaccine Trials, Human Vaccines, vol.1, issue.1, pp.6-11, 2005. ,
DOI : 10.4161/hv.1.1.1424
Human Metapneumovirus Infection in Adults, The Pediatric Infectious Disease Journal, vol.27, issue.Supplement, pp.80-83, 2008. ,
DOI : 10.1097/INF.0b013e3181684dac
URL : http://pdfs.journals.lww.com/pidj/2008/10001/Human_Metapneumovirus_Infection_in_Adults.9.pdf?token=method|ExpireAbsolute;source|Journals;ttl|1503149717718;payload|mY8D3u1TCCsNvP5E421JYK6N6XICDamxByyYpaNzk7FKjTaa1Yz22MivkHZqjGP4kdS2v0J76WGAnHACH69s21Csk0OpQi3YbjEMdSoz2UhVybFqQxA7lKwSUlA502zQZr96TQRwhVlocEp/sJ586aVbcBFlltKNKo+tbuMfL73hiPqJliudqs17cHeLcLbV/CqjlP3IO0jGHlHQtJWcICDdAyGJMnpi6RlbEJaRheGeh5z5uvqz3FLHgPKVXJzdvEFnVrrJ5mORgYGWx8uf3EHHm+yV6aVbDHz4jbzC0NA=;hash|OyuIx/rC1G/u7O3Zi5cqYw==
RSV infection in the adult population, Manag Care, vol.17, issue.11, pp.13-18, 2008. ,
Human parainfluenza virus in patients with influenza-like illness from Central and South America during 2006-2010, Influenza and Other Respiratory Viruses, vol.31, issue.Suppl 1, pp.217-244, 2014. ,
DOI : 10.1097/INF.0b013e31823386f1
Comparison of severe pneumonia caused by Human metapneumovirus and respiratory syncytial virus in hospitalized children, Indian J Pathol Microbiol, vol.57, pp.413-420, 2014. ,
Respiratory syncytial virus- and human metapneumovirus-associated emergency department and hospital burden in adults, Influenza and Other Respiratory Viruses, vol.31, issue.10 Suppl, pp.347-52, 2014. ,
DOI : 10.1086/653202
Co-Infections with Influenza and Other Respiratory Viruses, Adv Exp Med Biol, vol.756, pp.291-301, 2013. ,
DOI : 10.1007/978-94-007-4549-0_36
Evaluation of viral co-infections in hospitalized and non-hospitalized children with respiratory infections using microarrays, Clinical Microbiology and Infection, vol.19, issue.8, pp.772-77, 2013. ,
DOI : 10.1111/1469-0691.12015
Influenza A viruses dual and multiple infections with other respiratory viruses and risk of hospitalisation and mortality, Influenza and Other Respiratory Viruses, vol.16, issue.1, pp.1079-1087, 2013. ,
DOI : 10.1002/jmv.20246
Clinical Disease Severity of Respiratory Viral Co-Infection versus Single Viral Infection: A Systematic Review and Meta-Analysis, PLoS ONE, vol.4, issue.6, p.99392, 2014. ,
DOI : 10.1371/journal.pone.0099392.s002
Single, dual and multiple respiratory virus infections and risk of hospitalization and mortality, Epidemiology and Infection, vol.129, issue.01, pp.37-47, 2015. ,
DOI : 10.1371/journal.pone.0009025
Is virus coinfection a predictor of severity in children with viral respiratory infections?, Clinical Microbiology and Infection, vol.21, issue.3, pp.264-265, 2015. ,
DOI : 10.1016/j.cmi.2014.08.024
Rhinovirus and Respiratory Syncytial Virus in Wheezing Children Requiring Emergency Care, American Journal of Respiratory and Critical Care Medicine, vol.89, issue.3, pp.785-90, 1999. ,
DOI : 10.1093/intimm/4.4.493
Evaluation of the Efficacy of Prednisolone in Early Wheezing Induced by Rhinovirus or Respiratory Syncytial Virus, The Pediatric Infectious Disease Journal, vol.25, issue.6, pp.482-490, 2006. ,
DOI : 10.1097/01.inf.0000215226.69696.0c
Human rhinoviruses, allergy, and asthma: a clinical approach, Medicina (Kaunas), vol.45, pp.839-886, 2009. ,
Do early-life viral infections cause asthma?, Journal of Allergy and Clinical Immunology, vol.125, issue.6, pp.1202-1207, 2010. ,
DOI : 10.1016/j.jaci.2010.01.024
Rhinovirus-induced bronchiolitis and asthma development, Pediatric Allergy and Immunology, vol.64, issue.4, pp.350-355, 2011. ,
DOI : 10.1111/j.1398-9995.2009.02022.x
Adolescent asthma after rhinovirus and respiratory syncytial virus bronchiolitis, Pediatric Pulmonology, vol.185, issue.7, pp.633-642, 2013. ,
DOI : 10.1164/rccm.201104-0660OC
Genetic variability of attachment (G) and Fusion (F) protein genes of human metapneumovirus strains circulating during 2006-2009 in Kolkata, Eastern India, Virology Journal, vol.8, issue.1, p.67, 2006. ,
DOI : 10.1186/1743-422X-8-67
Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade, Journal of Clinical Virology, vol.58, issue.3, pp.541-548, 2013. ,
DOI : 10.1016/j.jcv.2013.08.029
Phase 1 Study of the Safety and Immunogenicity of a Live, Attenuated Respiratory Syncytial Virus and Parainfluenza Virus Type 3 Vaccine in Seronegative Children, The Pediatric Infectious Disease Journal, vol.31, issue.2, pp.109-123, 2012. ,
DOI : 10.1097/INF.0b013e31823386f1
Safety and infectivity of two doses of live-attenuated recombinant cold-passaged human parainfluenza type 3 virus vaccine rHPIV3cp45 in HPIV3-seronegative young children, Vaccine, vol.31, issue.48, pp.5706-5718, 2013. ,
DOI : 10.1016/j.vaccine.2013.09.046
Genetic stability of RSV-F expression and the restricted growth phenotype of a live attenuated PIV3 vectored RSV vaccine candidate (MEDI-534) following restrictive growth in human lung cells, Vaccine, vol.31, issue.36, pp.3756-62, 2013. ,
DOI : 10.1016/j.vaccine.2013.04.015
A Recombinant G Protein Plus Cyclosporine A???Based Respiratory Syncytial Virus Vaccine Elicits Humoral and Regulatory T Cell Responses against Infection without Vaccine-Enhanced Disease, The Journal of Immunology, vol.77, issue.11, pp.1721-1752, 2016. ,
DOI : 10.1128/JVI.77.11.6580-6584.2003
ABSTRACT, Clinical and Vaccine Immunology, vol.23, issue.3, pp.186-194, 2016. ,
DOI : 10.1128/CVI.00037-16
First case in Italy of acquired resistance to oseltamivir in an immunocompromised patient with influenza A/H1N1v infection, Journal of Clinical Virology, vol.48, issue.3, pp.220-222, 2010. ,
DOI : 10.1016/j.jcv.2010.03.027
Monitoring and Characterization of Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, Japan, 2009???2010, Emerging Infectious Diseases, vol.17, issue.3, pp.470-479, 2009. ,
DOI : 10.3201/eid1703.101188
Mixtures of Oseltamivir-sensitive and -resistant Pandemic Influenza A/H1N1/2009 Viruses in Immunocompromised Hospitalized Children, The Pediatric Infectious Disease Journal, vol.30, issue.7, pp.625-632, 2011. ,
DOI : 10.1097/INF.0b013e31820929ab
Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives, The Lancet Infectious Diseases, vol.12, issue.3, pp.240-248, 2012. ,
DOI : 10.1016/S1473-3099(11)70318-8
Palivizumab???Resistant Human Respiratory Syncytial Virus Infection in Infancy, Clinical Infectious Diseases, vol.51, issue.2, pp.185-193, 2010. ,
DOI : 10.1086/653534
Analysis of Respiratory Syncytial Virus Preclinical and Clinical Variants Resistant to Neutralization by Monoclonal Antibodies Palivizumab and/or Motavizumab, The Journal of Infectious Diseases, vol.78, issue.Pt 3, pp.674-82, 2011. ,
DOI : 10.1128/JVI.78.18.9837-9841.2004
Detection of respiratory syncytial virus fusion protein variants between 2009 and 2012 in China, Archives of Virology, vol.276, issue.5, pp.1089-98, 2014. ,
DOI : 10.1074/jbc.M102633200
Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein, Virology, vol.454, issue.455, pp.454-55139, 2014. ,
DOI : 10.1016/j.virol.2014.02.010
Molecular characterization of respiratory syncytial viruses infecting children reported to have received palivizumab immunoprophylaxis, Journal of Clinical Virology, vol.65, pp.26-31, 2015. ,
DOI : 10.1016/j.jcv.2015.01.016
Cross-neutralization of four paramyxoviruses by a human monoclonal antibody, Nature, vol.1, issue.7467, pp.439-482, 2013. ,
DOI : 10.1007/BF01721323
Genome-wide diversity and selective pressure in the human rhinovirus, Virology Journal, vol.4, issue.1, p.40, 2007. ,
DOI : 10.1186/1743-422X-4-40
Phylogenetic Relationships and Molecular Adaptation Dynamics of Human Rhinoviruses, Molecular Biology and Evolution, vol.22, issue.4, pp.969-81, 2009. ,
DOI : 10.1093/molbev/msi097
Population Structure and Evolution of Rhinoviruses, PLoS ONE, vol.80, issue.22, p.88981, 2014. ,
DOI : 10.1371/journal.pone.0088981.s010
Coronaviruses ??? drug discovery and therapeutic options, Nature Reviews Drug Discovery, vol.351, issue.5, pp.327-374, 2016. ,
DOI : 10.1126/science.aad1283
Coronavirus Escape from Heptad Repeat 2 (HR2)-Derived Peptide Entry Inhibition as a Result of Mutations in the HR1 Domain of the Spike Fusion Protein, Journal of Virology, vol.82, issue.5, pp.2580-2585, 2008. ,
DOI : 10.1128/JVI.02287-07
Affiliations 1. Asha Mary Abraham, Christian Medical College ,
Centre National de référence de la grippe ,
Children's Research Hospital ,
The Chinese University of Hong Kong SAR ,
National Institute for Communicable Diseases (NICD) ,
Government of the Northwest Territories ,
The University of Hong Kong ,
Addenbrookes Hospital ,
British Columbia Centre for Disease Prevention and Control ,
The University of Hong Kong ,
Centre for Cellular and Molecular Platforms ,
John's Medical College Hospital ,
Centre for Children's Health Research ,
National Institute for Communicable Diseases ,