Artemisinin Resistance in Cambodia 1 Study C. Evidence of artemisinin-resistant malaria in western Cambodia, N Engl J Med, vol.359, issue.24, pp.2619-2639, 2008. ,
Artemisinin resistance in Plasmodium falciparum malaria, N Engl J Med, vol.361, issue.5, pp.455-67, 2009. ,
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria, Nature, vol.505, issue.7481, pp.50-55, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00921203
Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study, Lancet, vol.379, issue.9830, pp.1960-1966, 2012. ,
In vivo susceptibility of Plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam Malar J, vol.11, issue.1, p.355, 2012. ,
Spread of artemisinin resistance in Plasmodium falciparum malaria, N Engl J Med, vol.371, issue.5, pp.411-434, 2014. ,
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker, Lancet Infect Dis, vol.15, issue.4, pp.415-436, 2015. ,
A worldwide map of Plasmodium falciparum K13-propeller polymorphisms, N Engl J Med, vol.374, issue.25, pp.2453-64, 2016. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01336483
Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common, Malar J, vol.11, p.418, 2012. ,
Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of September 2012 meeting, Malar J, vol.11, p.424, 2012. ,
An assessment of the supply, programmatic use, and regulatory issues of single low-dose primaquine as a Plasmodium falciparum gametocytocide for subSaharan Africa, Malar J, vol.14, p.204, 2015. ,
Single low dose primaquine (0.25 mg/kg) does not cause clinically significant haemolysis in G6PD deficient subjects, PLoS One, vol.11, p.151898, 2016. ,
Adding a single low-dose of primaquine (0.25 mg/kg) to artemetherlumefantrine did not compromise treatment outcome of uncomplicated Plasmodium falciparum malaria in Tanzania: a randomized, single-blinded clinical trial, Malar J, vol.15, p.435, 2016. ,
Development of a pharmacovigilance safety monitoring tool for the rollout of single low-dose primaquine and artemether-lumefantrine to treat Plasmodium falciparum infections in Swaziland: a pilot study, Malar J, vol.15, issue.1, p.384, 2016. ,
, The World Health Organization. Guidelines for the Treatment of Malaria, p.42, 2015.
An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia, BMC Med, vol.14, issue.1, p.171, 2016. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01739357
Performance of the CareStart G6PD deficiency screening test, a point-of-care diagnostic for primaquine therapy screening, PLoS One, vol.6, issue.12, p.28357, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00741113
G6PD deficiency in Plasmodium falciparum and Plasmodium vivax malaria-infected Cambodian patients, Malar J, vol.12, p.171, 2013. ,
Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria, Bull World Health Organ, vol.84, issue.12, pp.956-64, 2006. ,
Impact and lessons learned from mass drug administrations of malaria chemoprevention during the Ebola outbreak in, PLoS One, vol.11, issue.8, p.161311, 2014. ,
Factors associated with appropriate home management of uncomplicated malaria in children in Kassena-Nankana district of Ghana and implications for community case management of childhood illness: a cross-sectional study, BMC Public Health, vol.15, p.458, 2015. ,
Souls of the ancestor that knock us out' and other tales. A qualitative study to identify demand-side factors influencing malaria case management in Cambodia, Malar J, vol.11, p.335, 2012. ,
Access to artemisinin combination therapy for malaria in remote areas of Cambodia, Malar J, vol.7, p.96, 2008. ,
Malaria treatment-seeking behaviour and related factors of Wa ethnic minority in Myanmar: a cross-sectional study, Malar J, vol.11, p.417, 2012. ,
Improving malaria home treatment by training drug retailers in rural Kenya, Trop Med Int Health, vol.9, issue.4, pp.451-60, 2004. ,
Age, weight, and CYP2D6 genotype are major determinants of primaquine pharmacokinetics in African children, Antimicrob Agents Chemother, issue.5, p.61, 2017. ,
The value of plasmoquine as a gametocide in sub-tertian malaria, Trans R Soc Trop Med Hyg, vol.40, issue.4, pp.447-50, 1947. ,
Some observations on the action of quinine, atebrin, and plasmoquine on Plasmodium vivax, Trans R Soc Trop Med Hyg, vol.42, issue.5, pp.443-54, 1949. ,
The effect of a single dose of primaquine on the gametocytes, gametogony and sporogony of Laverania falciparum, Bull World Health Organ, vol.24, pp.451-457, 1961. ,
Gametocytocidal and sporontocidal effects of primaquine upon two strains of Plasmodium falciparum, Mil Med, vol.134, issue.10, pp.802-821, 1969. ,
Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial, Lancet Infect Dis, vol.16, pp.674-84, 2016. ,
Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria, Malar J, vol.13, p.483, 2014. ,
Predicting mosquito infection from Plasmodium falciparum gametocyte density and estimating the reservoir of infection, Elife, vol.2, p.626, 2013. ,
Infectivity to mosquitoes of Plasmodium falciparum as related to gametocyte density and duration of infection, Am J Trop Med Hyg, vol.4, issue.5, pp.781-790, 1955. ,
Infectious reservoir of Plasmodium infection in Mae Hong Son Province, north-west Thailand, Malar J, vol.3, p.34, 2004. ,
Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: a randomised, double-blind, placebocontrolled trial, BMC Med, vol.14, p.40, 2016. ,
The gametocytocidal efficacy of different single doses of primaquine with dihydroartemisinin-piperaquine in asymptomatic parasite carriers in the Gambia: a randomized controlled trial, EBioMedicine, vol.13, pp.348-55, 2016. ,
Primaquine: the risks and the benefits, Malar J, vol.13, p.418, 2014. ,
Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial, Lancet Infect Dis, vol.14, issue.2, pp.130-139, 2013. ,
In Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (G6PD A-) individuals, Antimicrob Agents Chemother, vol.54, issue.5, pp.1762-1770, 2010. ,
Increased risk of early vomiting among infants and young children treated with dihydroartemisinin-piperaquine compared with artemether-lumefantrine for uncomplicated malaria, Am J Trop Med Hyg, vol.83, issue.4, pp.873-878, 2010. ,
A randomized comparison of the efficacy and tolerability of three artemisinin-based combination treatments for children with acute falciparum malaria in The Democratic Republic of Congo, Antimicrob Agents Chemother, vol.58, issue.9, pp.5528-5564, 2014. ,
Safety profile of Coartem: the evidence base, Malar J, vol.8, issue.1, p.6, 2009. ,
Tolerability and safety of artesunate-amodiaquine and artemetherlumefantrine fixed dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria: two open-label, randomized trials in Nimba County, Liberia Malar J, vol.12, p.250, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-00854378
Elevated levels of methaemoglobin in Tanzanian children with severe and uncomplicated malaria, Trans R Soc Trop Med Hyg, vol.90, issue.2, pp.147-51, 1996. ,
Tolerability and safety of weekly primaquine against relapse of Plasmodium vivax in Cambodians with glucose-6-phosphate dehydrogenase deficiency, BMC Med, vol.13, p.203, 2015. ,
The rise and fall of the antimalarial Lapdap: a lesson in pharmacogenetics, Lancet, vol.376, issue.9742, pp.739-780, 2010. ,
History of malaria treatment as a predictor of subsequent subclinical parasitaemia: a cross-sectional survey and malaria case records from three villages in Pailin, western Cambodia, Malar J, vol.15, p.240, 2016. ,
G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications, Br J Haematol, vol.164, issue.4, pp.469-80, 2014. ,
G6PD: population genetics and clinical manifestations, Blood Rev, vol.10, issue.1, pp.45-52, 1996. ,
Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya, BMC Med Genet, vol.15, p.93, 2014. ,
Spatial distribution of G6PD deficiency variants across malaria-endemic regions, Malar J, vol.12, p.418, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00907126
The prevalence of glucose-6-phosphate dehydrogenase deficiency in Gambian school children, Malar J, vol.13, p.148, 2014. ,
Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility, Eur J Hum Genet, vol.17, issue.8, pp.1080-1085, 2009. ,
Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance, Science, vol.293, issue.5529, pp.455-62, 2001. ,
Red cell glucose-6-phosphate dehydrogenase status and pyruvate kinase activity in a Nigerian population, Trop Med Int Health, vol.5, issue.2, pp.119-142, 2000. ,
Comparison of quantitative and qualitative tests for glucose-6-phosphate dehydrogenase deficiency, Am J Trop Med Hyg, vol.91, issue.4, pp.854-61, 2014. ,
Evaluation of the diagnostic accuracy of CareStart G6PD deficiency Rapid Diagnostic Test (RDT) in a malaria endemic area in Ghana, Africa PloS One, vol.10, issue.4, p.125796, 2015. ,
Molecular heterogeneity of glucose-6-phosphate dehydrogenase deficiency in Burkina Faso: G-6-PD betica selma and santamaria in people with symptomatic malaria in Ouagadougou, Mediterr J Hematol Infect Dis, vol.8, issue.1, p.2016029, 2016. ,
Mutation analysis of glucose-6phosphate dehydrogenase (G6PD) variants in Costa Rica, Hum Genet, vol.87, issue.4, pp.462-466, 1991. ,
Genetic heterogeneity of glucose-6-phosphate dehydrogenase deficiency in south-east Sicily, Ann Hum Genet, vol.61, pp.229-263, 1997. ,
Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria, Malar J, vol.15, p.13, 2016. ,
The inter-and intra-tribal distribution of red cell G6PD phenotypes in Sudan, Hum Hered, vol.33, issue.1, pp.39-43, 1983. ,
A study of some genetic characteristics of the population of the Sudan, Ann Hum Biol, vol.5, issue.6, pp.569-75, 1978. ,
Glucose-6-phosphate dehydrogenase status and risk of hemolysis in Plasmodium falciparum-infected African children receiving single-dose primaquine, Antimicrob Agents Chemother, vol.58, issue.8, pp.4971-4974, 2014. ,
Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate, PLoS One, vol.2, issue.10, p.1023, 2007. ,
Severe anemia in Malawian children, N Engl J Med, vol.358, issue.9, pp.888-99, 2008. ,
Decreased prevalence of anemia in highland areas of low malaria transmission after a 1-year interruption of transmission, Clin Infect Dis, vol.54, issue.2, pp.178-84, 2012. ,
Prevalence of anaemia in patients attending an outpatient clinic in western Rift Valley in Kenya during a low malaria season, East Afr Med J, vol.76, issue.5, pp.251-255, 1999. ,
Impact of schistosome infection on Plasmodium falciparum malariometric indices and immune correlates in school age children in Burma Valley, PLoS Negl Trop Dis, vol.4, issue.11, p.882, 2010. ,
Clinical signs for the recognition of children with moderate or severe anaemia in western Kenya, Bull World Health Organ, vol.75, issue.1, pp.97-102, 1997. ,
Anemia and malaria at different altitudes in the western highlands of Kenya, Acta Trop, vol.91, issue.2, pp.167-75, 2004. ,
Nutritional status of young children with inherited blood disorders in western Kenya, Am J Trop Med Hyg, vol.90, issue.5, pp.955-62, 2014. ,
Patterns of malaria indices across three consecutive seasons in children in a highly endemic area of West Africa: a three times-repeated cross-sectional study, Malar J, vol.13, p.199, 2014. ,
Hematological indices in Malian children change significantly during a malaria season and with increasing age: implications for malaria epidemiological studies, Am J Trop Med Hyg, vol.95, issue.2, pp.368-72, 2016. ,
A randomised, double-blind, placebo-controlled trial of atovaquoneproguanil vs. sulphadoxine-pyrimethamine in the treatment of malarial anaemia in Zambian children, Trop Med Int Health, vol.11, issue.11, pp.1643-52, 2006. ,
Simplified estimation of age-specific reference intervals for skewed data, Stat Med, vol.16, issue.24, pp.2785-803, 1997. ,
Smooth centile curves for skew and kurtotic data modelled using the Box-Cox power exponential distribution, Stat Med, vol.23, pp.3053-76, 2004. ,
Factors determining the occurrence of submicroscopic malaria infections and their relevance for control, Nat Commun, vol.3, p.1237, 2012. ,
Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine, Malar J, vol.9, p.57, 2010. ,
Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial, Lancet Infect Dis, vol.16, issue.6, pp.674-84, 2016. ,
The burden of polyparasitism among primary schoolchildren in rural and farming areas in Zimbabwe, Trans R Soc Trop Med Hyg, vol.102, issue.10, pp.1039-1084, 2008. ,
Transfusion and treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial, Trials, vol.16, p.593, 2015. ,
Developing regional weight-for-age growth references for malariaendemic countries to optimize age-based dosing of antimalarials, Bull World Health Organ, vol.93, issue.2, pp.74-83, 2015. ,