, Document WHO/HTM/GMP/ 2016, vol.2, 2016.

T. Kesteman, S. A. Rafalimanantsoa, and H. Razafimandimby, Multiple causes of an unexpected malaria outbreak in a hightransmission area in Madagascar, Malaria Journal, vol.15, issue.1, 2016.

T. Kesteman, M. Randrianarivelojosia, and C. Mattern, Nationwide evaluation of malaria infections, morbidity, mortality, and coverage of malaria control interventions in Madagascar, Malaria Journal, vol.13, issue.1, p.465, 2014.

D. Rapport, Enquête sur les indicateurs du paludismè a Madagascar, 2016.

H. Ranson and N. Lissenden, Insecticide resistance in african anopheles mosquitoes: a worsening situation that needs urgent action to maintain malaria control, Trends in Parasitology, vol.32, issue.3, pp.187-196, 2016.

D. Randriantsimaniry, Vector control in the epidemics of the Madagascar highlands, Santé, vol.5, issue.6, pp.392-396, 1995.

J. Hamon, J. Mouchet, G. Chauvet, and R. Lumaret, Review of 14 years of malaria control in the french-speaking countries of tropical africa and in madagascar. considerations on the persistence of transmission and future prospects, vol.56, pp.933-971, 1963.

S. Mercier and J. B. Razafindrakoto, Results of 3 years' campaigning of disinsectization of homes in Tanarive, vol.46, pp.463-473, 1953.

M. Razanamparany, A. Bosman, N. Ravelomanana, F. Randriamiharisoa, and L. Razafimantsoa, The malaria epidemic in Antananarivo observed from Pediatric Service "A" of the Befelatanana General Hospital, Parassitologia, vol.31, issue.1, pp.89-99, 1989.

M. S. Razanamparany, F. A. Randriamiharisoa, N. J. Razanamparany, and V. Ramialimanana, The malaria epidemic in Antananarivo from 1983 to 1994 as seen through the Pediatric Service A in the Befelatanana General Hospital, Santé, vol.5, issue.6, pp.382-385, 1995.

D. Fontenille and I. Rakotoarivony, Reappearance of anopheles funestus as a malaria vector in the antananarivo region, Madagascar, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.82, issue.4, pp.644-645, 1988.

J. P. Lepers, D. Fontenille, M. D. Andriamangatiana-rason, P. Deloron, and P. Coulanges, Ecological factors in the renewed outbreak of malaria in Madagascar, Bulletin de Société de Pathologie Exotique, vol.83, pp.330-341, 1990.

L. Marrama, E. Rajaonarivelo, S. Laventure, and P. Rabarison, Anopheles funestus and rice culture on the Plateau of Madagascar, Cahiers/Santé, vol.5, issue.6, pp.415-419, 1995.

D. Fontenille and F. Simard, Unravelling complexities in human malaria transmission dynamics in Africa through a comprehensive knowledge of vector populations, Comparative Immunology, Microbiology & Infectious Diseases, vol.27, issue.5, pp.357-375, 2004.

B. Greenwood and K. Koram, Malaria control in Africa: Progress but still much to do, The Lancet, vol.383, issue.9930, pp.1703-1704, 2014.

S. Sougoufara, S. M. Diédhiou, and S. Doucouré, Biting by Anopheles funestus in broad daylight after use of long-lasting insecticidal nets: A new challenge to malaria elimination, Malaria Journal, vol.13, issue.1, p.125, 2014.

, BioMed Research International

J. Trape, A. Tall, and N. Diagne, Malaria morbidity and pyrethroid resistance after the introduction of insecticidetreated bednets and artemisinin-based combination therapies: a longitudinal study, The Lancet Infectious Diseases, vol.11, issue.12, pp.925-932, 2011.
URL : https://hal.archives-ouvertes.fr/pasteur-00618289

M. Zaim, A. Aitio, and N. Nakashima, Safety of pyrethroidtreated mosquito nets, Medical and Veterinary Entomology, vol.14, issue.1, pp.1-5, 2000.

J. Hemingway, H. Ranson, and A. Magill, Averting a malaria disaster: Will insecticide resistance derail malaria control?, The Lancet, vol.387, issue.10029, pp.1785-1788, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01998408

H. Ranson, R. N'guessan, J. Lines, N. Moiroux, Z. Nkuni et al., Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?, Trends in Parasitology, vol.27, issue.2, pp.91-98, 2011.

J. Ratovonjato, M. Randrianarivelojosia, and M. E. Rakotondrainibe, Entomological and parasitological impacts of indoor residual spraying with DDT, alphacypermethrin and deltamethrin in the western foothill area of Madagascar, Malaria Journal, vol.13, issue.1, 2014.
URL : https://hal.archives-ouvertes.fr/pasteur-01076886

, Plan stratégique national de lutte contre le paludismè a Madagascar, 2017.

J. Rakotoson, C. M. Fornadel, and A. Belemvire, Insecticide resistance status of three malaria vectors, Anopheles gambiae (s.l.), An. funestus and An. mascarensis, from the south, central and east coasts of Madagascar, Parasites & Vectors, vol.10, issue.1, 2017.

, President's Malaria Initiative Country Insecticide Susceptibility Summaries, PMI Report, 2016.

M. T. Gillies and D. De-meillon, The Anophelinae of Africa South of the Sahara, Publications of the South African Institute for Medical Research, vol.54, p.343, 1968.

T. N. Nepomichene, L. Andrianaivolambo, S. Boyer, and C. Bourgouin, Efficient method for establishing F1 progeny from wild populations of Anopheles mosquitoes, Malaria Journal, vol.16, issue.1, p.21, 2017.
URL : https://hal.archives-ouvertes.fr/pasteur-01441061

/. Editor, Test procedures for insecticide resistance monitoring in malaria vector mosquitoes, 2016.

S. Randriamaherijaona, H. J. Velonirina, and S. Boyer, Susceptibility status of Anopheles arabiensis (Diptera: Culicidae) commonly used as biological materials for evaluations of malaria vector control tools in Madagascar, Malaria Journal, vol.15, issue.1, 2016.

W. G. Brogdon, J. C. Mcallister, and J. Vulule, Heme peroxidase activity measured in single mosquitoes identifies individuals expressing an elevated oxidase for insecticide resistance, Journal of the American Mosquito Control Association, vol.13, issue.3, pp.233-237, 1997.

J. Hemingway and W. G. Brogdon, Techniques to Detect Insecticide Resistance Mechanisms (Field and Laboratory Manual), 1998.

M. L. Sangba, T. Deketramete, S. P. Wango, M. Kazanji, M. Akogbeto et al., Insecticide resistance status of the Anopheles funestus population in Central African Republic: A challenge in the war, Parasites & Vectors, vol.9, issue.1, 2016.

M. L. Dustin, Visualizing Immune System Complexity, Science Signaling, vol.2, issue.66, pp.4-4, 2009.

A. Cohuet, F. Simard, J. Toto, P. Kengne, M. Coetzee et al., Species identification within the Anopheles funestus group of malaria vectors in Cameroon and evidence for a new species, The American Journal of Tropical Medicine and Hygiene, vol.69, issue.2, pp.200-205, 2003.

N. Cuamba, J. C. Morgan, H. Irving, A. Steven, and C. S. Wondji, High level of pyrethroid resistance in an Anopheles funestus population of the chokwe district in mozambique, PLoS ONE, vol.5, issue.6, 2010.

M. E. Rakotondraibe, G. L. Goff, and E. Rajaonarivelo, Insecticide sensitivity in malaria vectors in high altitude Madagascar after five years of vector control, Institut Pasteur de Madagascar, vol.66, issue.1-2, pp.32-35, 2000.

J. Ratovonjato, G. L. Goff, E. Rajaonarivelo, E. M. Rakotondraibe, and V. Robert, Recent observations on the sensitivity to pyrethroids and DDT of Anopheles arabiensis and Anopheles funestus in the central Highlands of Madagascar, Institut Pasteur de Madagascar, vol.69, issue.1-2, pp.63-69, 2003.

, Les irrigations en 1925 dans la plaine de Marovoay, Extrait du bulletinéconomiquebulletinéconomique de Madagascar, 23e Année, 1926.

J. D. Lines and N. S. Nassor, DDT resistance in Anopheles gambiae declines with mosquito age, Medical and Veterinary Entomology, vol.5, issue.3, pp.261-265, 1991.

C. Czeher, R. Labbo, I. Arzika, and J. Duchemin, Evidence of increasing Leu-Phe knockdown resistance mutation in Anopheles gambiae from Niger following a nationwide long-lasting insecticide-treated nets implementation, Malaria Journal, vol.7, issue.189, 2008.

J. M. Vulule, R. F. Beach, F. K. Atieli, J. M. Roberts, D. L. Mount et al., Reduced susceptibility of Anopheles gambiae to permethrin associated with the use of permethrin-impregnated bednets and curtains in Kenya, Medical and Veterinary Entomology, vol.8, issue.1, pp.71-75, 1994.

C. Mulamba, J. M. Riveron, and S. S. Ibrahim, Widespread pyrethroid and DDT resistance in the major malaria vector anopheles funestus in East Africa is driven by metabolic resistance mechanisms, PLoS ONE, vol.9, issue.10, 2014.

, data?title selective=All&region selective=Abia&year selective=All&field non endemic value=0 Accessed, 2016.

R. Djouaka, H. Irving, Z. Tukur, and C. S. Wondji, Exploring mechanisms of multiple insecticide resistance in a population of the malaria vector Anopheles funestus in Benin, PLoS ONE, vol.6, issue.11, 2011.

M. O. Ndiath, A. Cailleau, and E. Orlandi-pradines, Emerging knock-down resistance in Anopheles arabiensis populations of Dakar, Senegal: First evidence of a high prevalence of kdr-e mutation in West African urban area, Malaria Journal, vol.14, issue.1, 2015.

M. O. Ndiath, K. Eiglmeier, M. L. Olé-sangba, I. Holm, M. Kazanji et al., Composition and genetics of malaria vector populations in the Central African Republic, Malaria Journal, vol.15, issue.1, p.387, 2016.
URL : https://hal.archives-ouvertes.fr/pasteur-01947697

, BioMed Research International 9

R. G. Kloke, E. Nhamahanga, R. H. Hunt, and M. Coetzee, Vectorial status and insecticide resistance of Anopheles funestus from a sugar estate in southern Mozambique, Parasites & Vectors, vol.4, issue.1, p.16, 2011.

J. M. Riveron, S. S. Ibrahim, and E. Chanda, The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa, BMC Genomics, vol.15, issue.1, p.817, 2014.

J. M. Riveron, H. Irving, and M. Ndula, Directionally selected cytochrome P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus, Proceedings of the National Acadamy of Sciences of the United States of America, vol.110, pp.252-257, 2013.