S. Chen, C. Xue, L. Yin, Q. Tang, G. Yu et al., Comparison of structures and anticoagulant activities of fucosylated chondroitin sulfates from different sea cucumbers, Carbohydr. Polym, vol.83, pp.688-695, 2011.

S. Chen, G. Li, N. Wu, X. Guo, N. Liao et al., Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates, Biochim. Biophys. Acta, vol.1830, pp.3054-3066, 2013.

M. Wu, S. M. Xu, J. H. Zhao, H. Kang, and H. Ding, Physicochemical characteristics and anticoagulant activities of low molecular weight fractions by free radical depolymerization of a fucosylated chondroitin sulfate from sea cucumber Thelenata ananas, Food Chem, vol.122, pp.716-723, 2010.

M. Wu, R. Huang, D. Wen, N. Gao, J. He et al., Structure and effect of sulfated fucose branches on anticoagulant activity of the fucosylated chondroitin sulfate from sea cucumber Thelenata ananas, Carbohydr. Polym, vol.87, pp.862-868, 2012.

N. Wu, X. Ye, X. Guo, N. Liao, X. Yin et al., Depolymerization of fucosylated chondroitin sulfate from sea cucumber, Pearsonothuria graeffei, via coirradiation, Carbohydr. Polym, vol.93, pp.604-614, 2013.

M. Ben-mansour, R. Balti, V. Ollivier, H. B. Jannet, F. Chaubet et al., Characterization and anticoagulant activity of a fucosylated chondroitin sulfate with unusually procoagulant effect from sea cucumber, Carbohydr. Polym, vol.174, pp.760-771, 2017.

A. C. Ribeiro, R. P. Vieira, P. A. Mourão, and B. Mulloy, A sulfated alpha-l-fucan from sea cucumber, Carbohydr. Res, vol.255, pp.225-240, 1994.

Y. Kariya, B. Mulloy, K. Imai, A. Tominaga, T. Kaneko et al., Isolation and partial characterization of fucan sulfates from the body wall of sea cucumber Stichopus japonicus and their ability to inhibit osteoclastogenesis, Carbohydr. Res, vol.339, pp.1339-1346, 2004.

S. Chen, Y. Hu, X. Ye, G. Li, G. Yu et al., Sequence determination and anticoagulant and antithrombotic activities of a novel sulfated fucan isolated from the sea cucumber Isostichopus badionotus, Biochim. Biophys. Acta, vol.1820, pp.989-1000, 2012.

L. Yu, X. Xu, C. Xue, Y. Chang, L. Ge et al., Enzymatic preparation and structural determination of oligosaccharides derived from sea cucumber (Acaudina molpadioides) fucoidan, Food Chem, vol.139, pp.702-709, 2013.

L. Yu, L. Ge, C. Xue, Y. Chang, C. Zhang et al., Structural study of fucoidan from sea cucumber Acaudina molpadioides: a fucoidan containing novel tetrafucose repeating unit, Food Chem, vol.142, pp.197-200, 2014.

L. Yu, C. Xue, Y. Chang, X. Xu, L. Ge et al., Structure elucidation of fucoidan composed of a novel tetrafucose repeating unit from sea cucumber Thelenota ananas, Food Chem, vol.146, pp.113-119, 2014.

Y. Chang, Y. Hu, L. Yu, D. J. Mcclements, X. Xu et al., Primary structure and chain conformation of fucoidan extracted from sea cucumber Holothuria tubulosa, Carbohydr. Polym, vol.136, pp.1091-1097, 2016.

L. Yu, C. Xue, Y. Chang, Y. Hu, X. Xu et al., Structure and rheological characteristics of fucoidan from sea cucumber Apostichopus japonicas, Food Chem, vol.180, pp.71-76, 2015.

S. Hu, G. Xia, J. Wang, Y. Wang, Z. Li et al., Fucoidan from sea cucumber protects against high-fat high-sucrose diet-induced hyperglycaemia and insulin resistance in mice, J. Funct. Foods, vol.10, pp.128-138, 2014.

Y. Zhang, S. Song, D. Song, H. Liang, W. Wang et al., Proliferative effects on neural stem/progenitor cells of a sulfated polysaccharide purified from the sea cucumber Stichopus japonicus, J. Biosci. Bioeng, vol.109, pp.67-72, 2010.

Y. Wang, W. Su, C. Zhang, C. Xue, Y. Chang et al., Protective effect of sea cucumber (Acaudina molpadioides) fucoidan against ethanol-inducedgastric damage, Food Chem, vol.133, pp.1414-1419, 2012.

X. Guo, X. Ye, Y. Sun, D. Wu, N. Wu et al., Ultrasound effects on the degradation kinetics, structure, and antioxidant activity of sea cucumber fucoidan, J. Agric. Food Chem, vol.62, pp.1088-1095, 2014.

T. Zuo, X. Li, Y. Chang, G. Duan, L. Yu et al., Dietary fucoidan of Acaudina molpadioides and its enzymatically degraded fragments could prevent intestinal mucositis induced by chemotherapy in mice, Food Funct, vol.6, pp.415-422, 2015.

H. Xu, J. Wang, Y. Chang, J. Xu, Y. Wang et al., Fucoidan from the sea cucumber Acaudina molpadioides exhibits anti-adipogenic activity by modulating the Wnt/?-catenin pathway and down-regulating the SREBP-1c expression, Food Funct, vol.5, pp.1547-1555, 2014.

T. S. Vo and S. K. Kim, Fucoidans as a natural bioactive ingredient for functional foods, J. Funct. Foods, vol.5, pp.16-27, 2013.

A. Bezeaud, M. H. Denninger, and M. C. Guillin, Interaction of human alpha-thrombin and gamma-thrombin with antithrombin III, protein C and thrombomodulin, Eur. J. Biochem, vol.153, pp.491-496, 1985.

Y. Wegrowski and F. X. Maquart, Cellulose acetate electrophoresis of glycosaminoglycanes, Methods Mol. Biol, vol.171, pp.175-179, 2001.

Z. Dische and L. B. Schettles, A specific color reaction of methylpentoses and a spectrophotometric micromethod for their determination, J. Biol. Chem, vol.175, pp.595-603, 1948.

T. Bitter and H. M. Muir, A modified uronic acid carbazole reaction, Anal. Biochem, vol.4, pp.330-334, 1962.

L. Gustafsson, Determination of ultramicro amounts of sulphate as methylene blueII: the reduction, Talanta, vol.4, pp.236-243, 1960.

V. Kuban, P. K. Dasgupta, and J. N. Marx, Nitroprusside and methylene blue methods for silicone membrane differentiated flow injection determination of sulfide in water and wastewater, Anal. Chem, vol.64, pp.36-43, 1992.

P. Saboural, F. Chaubet, F. Rouzet, F. Al-shoukr, R. Ben-azzouna et al., Purification of a low molecular weight Fucoidan for SPECT molecular imaging of myocardial infarction, Mar. Drugs, vol.12, pp.4851-4867, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01866736

M. Ben-mansour, M. Dhahri, I. Bertholon, V. Ollivier, I. Bataille et al., Characterization of a novel dermatan sulfate with high antithrombin activity from ray skin (Raja radula), Thromb. Res, vol.123, pp.887-894, 2009.

M. Ben-mansour, H. Majdoub, I. Bataille, M. S. Roudesli, M. Hassine et al., Polysaccharides from the skin of ray Raja radula. Partial characterization and anticoagulant activity, Thromb. Res, vol.123, pp.671-678, 2009.

M. Ben-mansour, M. Dhahri, L. Vénisse, M. Jandrot-perrus, F. Chaubet et al., Mechanism of thrombin inhibition by heparin cofactor II and antithrombin in the presence of the ray (Raja radula) skin dermatan sulfate, Thromb. Res, vol.123, pp.902-908, 2009.

H. C. Hemker, P. Giesen, R. Dieri, V. Regnault, E. De et al., Calibrated automated thrombin generation measurement in clotting plasma, Pathophysiol. Haemost. Thromb, vol.33, pp.4-15, 2003.

Y. Hu, S. Li, J. Li, X. Ye, T. Ding et al., Identification of a highly sulfated fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated tetrasaccharides units, Carbohydr. Polym, vol.134, pp.808-816, 2015.

M. Ben-mansour, M. Dhahri, M. Hassine, N. Ajzenberg, L. Venisse et al., Highly sulfated dermatan sulfate from the skin of the ray Raja montagui: anticoagulant activity and mechanism of action, Comp. Biochem. Physiol. B Biochem. Mol. Biol, vol.156, pp.206-215, 2010.

B. Matsuhiro, I. Osorio-román, and R. Torres, Vibrational spectroscopy characterization and anticoagulant activity of a sulfated polysaccharide from sea cucumber Athyonidium chilensis, Carbohydr. Polym, vol.88, pp.959-965, 2012.

R. J. Fonseca, G. R. Santos, and P. A. Mourão, Effects of polysaccharides enriched in 2,4-disulfated fucose units on coagulation, thrombosis and bleeding, Thromb. Haemost, vol.102, pp.829-836, 2009.

V. K. Morya, J. Kim, and E. K. Kim, Algal fucoidan: structural and size-dependent bioactivities and their perspectives, Appl. Microbiol. Biotechnol, vol.93, pp.71-82, 2012.

F. Haroun-bouhedja, M. Ellouali, C. Sinquin, and C. Boisson-vidal, Relationship between sulfate groups and biological activities of fucans, vol.100, pp.453-459, 2000.

S. You, C. Yang, H. Lee, and B. Y. Lee, Molecular characteristics of partially hydrolyzed fucoidans from sporophyll of Undaria pinnatifida and their in vitro anticancer activity, Food Chem, vol.119, pp.554-559, 2010.

P. A. Mourão, Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives, Curr. Pharm. Des, vol.10, pp.967-981, 2004.