The Hallmarks of Cancer, vol.100, pp.57-70, 2000. ,
Identification of receptor tyrosine kinase, discoidin domain receptor 1 (DDR1), as a potential biomarker for serous ovarian cancer, International Journal of Molecular Sciences, vol.12, pp.971-982, 2011. ,
Integrin signalling during tumour progression, Nat Rev Mol. Cell Biol, vol.5, pp.816-826, 2004. ,
In vivo functions of integrins: lessons from null mutations in mice Dean, Matrix Biol, vol.19, pp.203-209, 2000. ,
Integrin signaling: specificity and control of cell survival and cell cycle progression, Curr Opin Cell Biol, vol.9, pp.691-700, 1997. ,
Integrin activation takes shape, J Cell Biol, vol.158, pp.833-839, 2002. ,
Regulation of integrin activity and signalling, Biochimica et Biophysica Acta, vol.6, pp.431-444, 2009. ,
Function and interactions of integrins, Cell Tissue Research, vol.3, pp.285-298, 2001. ,
Integrins: bidirectional, allosteric signaling machines, Cell, vol.110, pp.673-687, 2000. ,
Integrins: versatility, modulation, and signaling in cell adhesion, Cell, vol.69, pp.11-25, 1992. ,
Evolution of snake venom disintegrins by positive Darwinian selection, Mol Biol Evol, vol.25, pp.2391-407, 2008. ,
Viper venom disintegrins and related molecules, Proc. Soc. Exp. Biol. Med, vol.219, pp.109-119, 1998. ,
The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion, Adv Protein Chem, vol.68, pp.29-63, 2004. ,
Two conformations of the integrin A-domain (I-domain): A pathway for activation, vol.3, pp.1333-1340, 1995. ,
The collagen receptor integrins have distinct ligand recognition and signaling functions, Matrix Biol, vol.19, pp.319-342, 2000. ,
Enhancing integrin ?1 inserted (I) domain affinity to ligand potentiates integrin ?1?1-mediated down-regulation of collagen synthesis, J Biol Chem, vol.287, pp.35139-35152, 2012. ,
Synthetic heterotrimeric collagen peptides as mimics of cell adhesion sites of the basement membrane, Biopolymers, vol.76, pp.34-47, 2004. ,
Disintegrins from snake venoms and their applications in cancer research and therapy, Curr Protein Pept Sci, vol.16, pp.532-580, 2015. ,
Functional characteristic of snake venom disintegrins: Potential therapeutic implication, Current Pharmaceutical Design, vol.11, pp.815-842, 2005. ,
Snake venom disintegrins: evolution of structure and function, Toxicon, vol.45, pp.1063-1074, 2005. ,
Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion, Am J Physiol, vol.264, pp.361-370, 1993. ,
Chlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumor invasion, Toxins (Basel), vol.7, pp.1079-101, 2015. ,
ATDB: a unidatabase platform for animal toxins, Nucleic Acids Res, vol.36, 2008. ,
Toxins and drug discovery, Toxicon, vol.92, pp.193-200, 2014. ,
Scorpion toxins as natural scaffolds for protein engineering, Biochemistry, vol.92, pp.6404-6408, 1995. ,
Scorpion venom peptides without disulfide bridges, IUBMB Life, vol.57, pp.13-21, 2005. ,
The first very short peptide from Buthus occitanus tunetanus inhibits tumor cell migration, proliferation and angiogenesis, Biochem Biophys Res Commun, issue.18, pp.30148-30155, 2018. ,
Kbot1, a three disulfide bridges toxin from Buthus occitanus tunetanus venom highly active on both SK and Kv channels, Peptides, vol.25, pp.637-682, 2004. ,
URL : https://hal.archives-ouvertes.fr/hal-01974093
purified from Buthus occitanus tunetanus venom, represents the first member of a novel ?-KTx subfamily, Peptides, vol.80, pp.4-8, 2016. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01375001
purified from Buthus occitanus tunetanus venom, represents the first member of a novel ?-KTx subfamily, Peptides, vol.80, pp.4-8, 2016. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01375001
Diphenhydramine-induced amnesia is mediated by Gi-protein activation, Neuroscience, vol.122, pp.471-478, 2003. ,
Novel purification of vitronectin from human plasma by heparin affinity chromatography, Cell. Struct. Funct, vol.13, pp.281-292, 1988. ,
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays, J. Immunol. Methods, vol.65, pp.55-63, 1983. ,
Effect of microtubule disruption on cell adhesion and spreading, Biochem.Biophys. Res. Commun, vol.246, pp.690-695, 1998. ,
Rigot, V. alphavbeta5/beta6 integrin suppression leads to a stimulation of alpha2beta1 dependent cell migration resistant to PI3K/Akt inhibition, Exp.Cell Res, vol.315, pp.1840-1849, 2009. ,
PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides, Nucleic. Acids. Res, vol.40, pp.288-293, 2012. ,
Ligand docking and binding site analysis with PyMOL and Autodock/Vina, J Comput Aided Mol Des, vol.24, pp.417-439, 2010. ,
Structural basis of integrin regulation and signaling, Annu Rev Immunol, vol.25, pp.619-647, 2007. ,
The structure of integrin ?1I domain in complex with a collagen-mimetic peptide, J Biol Chem, vol.288, pp.36796-809, 2013. ,
ENCoM server: exploring protein conformational space and the effect of mutations on protein function and stability, Nucleic Acids Res, vol.43, pp.395-400, 2015. ,
ZDOCK: an initial-stage protein-docking algorithm, Proteins, vol.52, pp.80-87, 2003. ,
ZRANK: reranking protein docking predictions with an optimized energy function, Proteins, vol.67, pp.1078-86, 2007. ,
The FoldX web server: an online force field, Nucleic Acids Res, pp.382-390, 2005. ,
A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6, J Comput Chem, vol.25, pp.1656-76, 2004. ,
PRODIGY: a web server for predicting the binding affinity of protein-protein complexes, Bioinformatics, vol.32, pp.3676-3678, 2016. ,
Interest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update, Oncotarget, vol.8, pp.86947-86968, 2017. ,
Interplay between cadherins and ?2?1 integrin differentially regulates melanoma cell invasion, Br J Cancer, vol.113, pp.1445-53, 2015. ,
Immunohistochemical analysis of integrins ?v?3, ?v?5 and ?5?1, and their ligands, fibrinogen, fibronectin, osteopontin and vitronectin, in frozen sections of human oral head and neck squamous cell carcinomas, Exp Ther Med, vol.2, pp.9-19, 2011. ,
Lebectin, a novel C-type lectin from Macrovipera lebetina venom, inhibits integrinmediated adhesion, migration and invasion of human tumour cells, Lab. Invest, vol.84, pp.573-581, 2004. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00875524
A neuronal cell line (PC12) expresses two beta 1-class integrins-alpha 1 beta 1 and alpha 3 beta 1-that recognize different neurite outgrowth-promoting domains in laminin, Neuron, vol.5, pp.651-62, 1990. ,
PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells, Matrix Biol, vol.32, pp.52-62, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00860245
A mechanism for divalent cation regulation of beta 3-integrins, J Biol Chem, vol.269, pp.960-967, 1994. ,
Integrin structure, allostery, and bidirectional signaling, Annu Rev Cell Dev Biol, vol.21, pp.381-410, 2005. ,
Acurhagin-C, an ECD disintegrin, inhibits integrin alphavbeta3-mediated human endothelial cell functions by inducing apoptosis via caspase-3 activation, Br J Pharmacol, vol.160, pp.1338-51, 2010. ,
Snake venom disintegrins and cell migration, Toxins (Basel), vol.2, pp.2606-2627, 2010. ,
Leberagin-C, A disintegrin-like/cysteine-rich protein from Macrovipera lebetina transmediterranea venom, inhibits alphavbeta3 integrin-mediated cell adhesion, Matrix Biol, vol.29, pp.117-126, 2010. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00621003
Mohamed el, A.; Naziha, M. Lebestatin, a disintegrin from Macrovipera venom, inhibits integrin-mediated cell adhesion, migration and angiogenesis, Lab. Invest, vol.85, pp.1507-1516, 2005. ,
Structural determinants of the selectivity of KTS-disintegrins for the alpha1beta1 integrin, FEBS Lett, vol.577, pp.478-82, 2004. ,
Crystal structure of the ?1?1 integrin I-domain: insights into integrin I-domain function, FEBS Lett, vol.452, pp.379-385, 1999. ,
Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, ?1?1 integrin and Staphylococcus aureus cna MSCRAMM, J Biol Chem, vol.274, pp.24906-24913, 1999. ,
Production, crystallization and preliminary X-ray analysis of the human integrin ?1I domain, Acta Crystallogr. D Biol. Crystallogr, vol.55, pp.1365-1367, 1999. ,
Jararhagin-derived RKKH peptidesinduce structural changes in ?1I domain of human integrin ?1?1, J. Biol. Chem, vol.279, pp.7962-7970, 2004. ,
Structural requirements of KTSdisintegrins for inhibition of alpha(1)beta(1) integrin, Biochem J, vol.417, pp.95-101, 2009. ,
Amino acid sequence and homology modeling of obtustatin, a novel non-RGD-containing short disintegrin isolated from the venom of Vipera lebetina obtusa, Protein Sci, vol.12, pp.366-371, 2003. ,
Inhibition of integrins ?v/?5-dependent functions in melanoma cells by an ECD-disintegrin acurhagin-C, Matrix Biol, vol.32, pp.152-159, 2013. ,
Crystal structure of the extracellular segment of integrin ?V?3, Science, vol.294, pp.339-384, 2001. ,
Crystal structure of the extracellular segment of integrin ?V?3 in complex with an Arg-Gly-Asp ligand, Science (NY), vol.296, pp.151-155, 2002. ,
Targeting ?1 inserted domain (I) of ?1?1 integrin by Lebetin 2 from M. lebetina transmediterranea venom decreased tumorigenesis and angiogenesis, Int J Biol Macromol, vol.117, pp.790-799, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01873764