L'interaction TET-OGT facilite la transcription en régulant la méthylation de l'histone H, Med Sci (Paris), vol.30, pp.619-640, 2014. ,
DOI : 10.1051/medsci/20143006007
URL : https://www.medecinesciences.org/articles/medsci/pdf/2014/07/medsci2014306-7p619.pdf
The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation, Cell Stem Cell, vol.13, pp.87-101, 2013. ,
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX, Nature, vol.497, pp.122-128, 2013. ,
Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins, PLoS One, vol.7, p.45031, 2012. ,
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation, Cancer Cell, vol.18, pp.553-67, 2010. ,
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells, Nature, vol.500, pp.222-228, 2013. ,
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development, Cell Stem Cell, vol.9, pp.166-75, 2011. ,
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis, Cancer Cell, vol.20, pp.25-38, 2011. ,
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes, Nature, vol.477, pp.606-616, 2011. ,
Combined deficiency of tet1 and tet2 causes epigenetic abnormalities but is compatible with postnatal development, Dev Cell, vol.24, pp.310-333, 2013. ,
Loss of Tet enzymes compromises proper differentiation of embryonic stem cells, Dev Cell, vol.29, pp.102-113, 2014. ,
TET2 deficiency inhibits mesoderm and hematopoietic differentiation in human embryonic stem cells, Stem Cells, vol.32, pp.2084-97, 2014. ,
The nexus of Tet1 and the pluripotency network, Cell Stem Cell, vol.12, pp.387-395, 2013. ,
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency, Nat Cell Biol, vol.15, pp.700-711, 2013. ,
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming, Cell Stem Cell, vol.12, pp.453-69, 2013. ,
Tet2 facilitates the derepression of myeloid target genes during CEBPalpha-induced transdifferentiation of pre-B cells, Mol Cell, vol.48, pp.266-76, 2012. ,
Mutation in TET2 in myeloid cancers, N Engl J Med, vol.360, pp.2289-301, 2009. ,
TET family proteins and their role in stem cell differentiation and transformation, Cell Stem Cell, vol.9, pp.193-204, 2011. ,
Le coeur des ARN non codants : un long chemin à découvrir, Med Sci (Paris), vol.31, pp.261-268, 2015. ,
leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23), Cancer Res, vol.62, pp.4075-80, 2002. ,
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation, Cell, vol.155, pp.1545-55, 2013. ,
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1, Science, vol.324, pp.930-935, 2009. ,
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain, Cell, vol.145, pp.423-457, 2011. ,
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair, Cell, vol.146, pp.67-79, 2011. ,
Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA, Nucleic Acids Res, vol.40, pp.9917-9943, 2012. ,
Reversing DNA methylation: mechanisms, genomics, and biological functions, Cell, vol.156, pp.45-68, 2014. ,
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA, Nat Chem Biol, vol.10, pp.574-81, 2014. ,
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity, Nature, vol.473, pp.343-351, 2011. ,
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells, Proc Natl Acad Sci, vol.111, pp.1361-1367, 2014. ,
Enhancer transcribed RNAs arise from hypomethylated, Tetoccupied genomic regions, Epigenetics, vol.8, pp.1303-1323, 2013. ,
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulo-monocytic differentiation of human hematopoietic progenitors, Blood, vol.118, pp.2551-2556, 2011. ,
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription, Nat Rev Mol Cell Biol, vol.14, pp.341-56, 2013. ,
DNA binding of the p21 repressor ZBTB2 is inhibited by cytosine hydroxymethylation, Biochem Biophys Res Commun, vol.446, pp.341-347, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01994537