Profil particulier des zymodèmes de Leishmania infantum causant la leishmaniose viscérale en Tunisie

Abstract : The isoenzymatic typing of 16 stocks of Leishmania, isolated from Tunisian visceral leishmaniasis (VL) cases, revealed that all strains belonged to Leishmania (L.) infantum species. Although zymodeme MON-1 was predictably the most frequent (9 cases), it came as a surprise that L. infantum MON-24 was responsible of about third of cases. This latter zymodeme, while previously reported in Tunisia, Algeria and Spain, was assumed to be a dermotropic and the few cases of VL that it caused occurred always in HIV infected patients. L. infantum MON-80, occasionally reported during both cutaneous and VL of immunocompetent infants was identified in 2 patients. This report confirms that in addition to the more common L. infantum MON-1, zymodeme MON-24 has a substantial role in generating VL in immunocompetent infants in Tunisia.
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https://hal-riip.archives-ouvertes.fr/pasteur-02044548
Contributor : Abdelhakim Ben Hassine <>
Submitted on : Thursday, February 21, 2019 - 3:24:59 PM
Last modification on : Tuesday, June 11, 2019 - 6:13:57 PM

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  • HAL Id : pasteur-02044548, version 1
  • PUBMED : 11889934

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K Aoun, A. Bouratbine, Z. Harrat, M Belkaïd, S Bel Hadj Ali. Profil particulier des zymodèmes de Leishmania infantum causant la leishmaniose viscérale en Tunisie. Bulletin de la Société de pathologie exotique , Masson, 2001, 94 (5), pp.375-7. ⟨pasteur-02044548⟩

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