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Tumour suppression by blocking palmitoylation

Abstract : Enhanced lysosomal degradation of the transmembrane protein programmed cell-death protein-1 ligand in tumour cells, enabled by blocking the protein’s post-translational lipid modification, promotes T-cell-mediated suppression of tumour growth in mice.
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Contributor : Michel Courcelles Connect in order to contact the contributor
Submitted on : Friday, May 17, 2019 - 6:08:21 PM
Last modification on : Monday, June 3, 2019 - 2:39:35 PM




Stephane Lefrancois. Tumour suppression by blocking palmitoylation. Nature Biomedical Engineering, Nature Publishing Group, 2019, 3 (4), pp.255-256. ⟨10.1038/s41551-019-0383-6⟩. ⟨pasteur-02133023⟩



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