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Enzyme catalysis under pressure

Nicolas Doucet 1, *
* Corresponding author
Abstract : A strategy using pressure was devised to structurally identify conformational transitions in protein ensembles, allowing the rational prediction of mutations that induce pressure-driven enzyme activation. These results highlight the power of flexibility–function analyses in protein engineering design and applications.
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Submitted on : Friday, August 30, 2019 - 3:48:43 PM
Last modification on : Wednesday, September 4, 2019 - 4:33:17 PM




Nicolas Doucet. Enzyme catalysis under pressure. Nature Catalysis, Nature Publishing Group, 2019, 2 (8), pp.646-647. ⟨10.1038/s41929-019-0326-3⟩. ⟨pasteur-02275285⟩



Les métriques sont temporairement indisponibles