L. J. Abraham and K. M. Kroeger, Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease, J Leukoc Biol, vol.66, pp.562-568, 1999.

D. Ahn, S. C. Crawley, and R. Hokari, TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation, Cell Physiol Biochem, vol.15, pp.29-40, 2005.

S. Ardestani, B. Li, and D. L. Deskins, Membrane versus soluble isoforms of TNF-? exert opposing effects on tumor growth and survival of tumor-associated myeloid cells, Cancer Res, vol.73, pp.3938-50, 2013.

N. Babapour, M. Mehramiz, and M. A. Rastgar, Association of TNF-308 G>A polymorphism located in tumor necrosis factor a with the risk of developing cervical cancer and results of pap smear, J Cell Biochem, vol.120, pp.5444-5452, 2019.

M. Z. Banday, H. M. Balkhi, and Z. Hamid, Tumor necrosis factor-? (TNF-?)-308G/A promoter polymorphism in colorectal cancer in ethnic Kashmiri population -A case control study in a detailed perspective, Meta Gene, vol.9, pp.128-164, 2016.

U. Berberoglu, E. Yildirim, and O. Celen, Serum levels of tumor necrosis factor alpha correlate with response to neoadjuvant chemotherapy in locally advanced breast cancer, Int J Biol Markers, vol.19, pp.130-134, 2004.

K. A. Bockerstett and R. J. Dipaolo, Regulation of gastric carcinogenesis by inflammatory cytokines, Cell Mol Gastroenterol Hepatol, vol.4, pp.47-53, 2017.

F. Bray, J. Ferlay, and I. Soerjomataram, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA A Cancer J Clin, vol.68, pp.394-424, 2018.

C. Cereda, S. Gagliardi, E. Cova, L. Diamanti, and M. Ceroni, The role of TNF-Alpha in ALS: New hypotheses for future therapeutic approaches, Amyotrophic Lateral Sclerosis. intechopen, 2012.

M. Coskun, J. T. Troelsen, and O. H. Nielsen, The role of CDX2 in intestinal homeostasis and inflammation, Biochim Biophys Acta, vol.1812, pp.283-292, 2011.

S. D'alfonso and P. M. Richiardi, A polymorphic variation in a putative regulation box of the TNFA promoter region, Immunogenetics, vol.39, pp.150-154, 1994.

L. C. Du and R. Gao, Role of TNF-? -308G/A gene polymorphism in gastric cancer risk: A case control study and meta-analysis, Turk J Gastroenterol, vol.28, pp.272-82, 2017.

K. Erturk, D. Tastekin, and M. Serilmez, Clinical significance of serum interleukin-29, interleukin-32, and tumor necrosis factor alpha levels in patients with gastric cancer, Tumour Biol, vol.37, pp.405-417, 2016.

A. Essadik, H. Jouhadi, and T. Rhouda, Polymorphisms of tumor necrosis factor Alpha in Moroccan patients with gastric pathology: New Single-Nucleotide Polymorphisms in TNF-? ?193 (G/A), Mediators Inflamm, 2015.

Y. Gao, Y. Yang, and F. Yuan, TNF?-YAP/p65-HK2 axis mediates breast cancer cell migration, Oncogenesis, vol.6, p.383, 2017.

T. Horiuchi, H. Mitoma, S. Harashima, H. Tsukamoto, and T. Shimoda, Transmembrane TNF-?: structure, function and interaction with anti-TNF agents, Rheumatology (Oxford), vol.49, pp.1215-1243, 2010.

W. H. Jang, Y. I. Yang, and S. S. Yea, The -238 tumor necrosis factor-alpha promoter polymorphism is associated with decreased susceptibility to cancers, Cancer Lett, vol.166, pp.41-47, 2001.

S. F. Josephs, T. E. Ichim, and M. Prince, Unleashing endogenous TNF-alpha as a cancer immunotherapeutic, J Transl Med, vol.16, p.242, 2018.

W. Kaluza, E. Reuss, and S. Grossmann, Different transcriptional activity and in vitro TNF-? production in psoriasis patients carrying the TNF-? 238A promoter polymorphism, J Investig Dermatol, vol.114, pp.1180-1183, 2000.

A. Karaman, H. Aydin, B. Geçki?nli?, D. N. Bi?ni?ci?, and ?. Pi?ri?m, Relation of chronic atrophic gastritis and intestinal metaplasia with Helicobacter pylori and tumor necrosis factor-? and macrophage migration inhibitory factor polymorphisms in a population of Easten Anatolia, Göztepe T?p Dergisi, vol.29, pp.12-21, 2014.

A. Koulis, A. Buckle, and A. Boussioutas, Precancerous lesions and gastric cancer: Current understanding, World J Gastrointest Oncol, vol.11, pp.665-673, 2019.

J. C. Machado, C. Figueiredo, and P. Canedo, A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma, Gastroenterology, vol.125, pp.364-71, 2003.

I. Martínez-reza, L. Díaz, R. García-becerra-r-;-mejías-luque, S. K. Lindén, and M. Garrido, Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors, Oncogene, vol.24, pp.1753-62, 2010.

R. Mlak, T. Powrózek, and A. Brzozowska, The relationship between TNF-? gene promoter polymorphism (? 1211 T > C), the plasma concentration of TNF-?, and risk of oral mucositis and shortening of overall survival in patients subjected to intensity-modulated radiation therapy due to head and neck cancer, Support Care Cancer, vol.28, pp.531-571, 2020.

L. Morningstar-wright, The Role of the TNF-alpha Inducing Protein (Tip?) in the Host Immune and Inflammatory Response to Helicobacter pylori Infection, 2018.

A. Mourtzikou, M. Alepaki, and M. Stamouli, Evaluation of serum levels of IL-6, TNF-?, IL-10, IL-2 and IL-4 in patients with chronic hepatitis, Inmunologia, vol.33, pp.41-50, 2014.

M. Oshima, H. Oshima, A. Matsunaga, and M. M. Taketo, Hyperplastic gastric tumors with spasmolytic polypeptide-expressing metaplasia caused by tumor necrosis factor-alpha-dependent inflammation in cyclooxygenase-2/ microsomal prostaglandin E synthase-1 transgenic mice, Cancer Res, vol.65, pp.9147-51, 2005.

F. Pan, J. Tian, and C. S. Ji, Association of TNF-?-308 and -238 polymorphisms with risk of cervical cancer: a meta-analysis, Asian Pac J Cancer Prev, vol.13, pp.5777-83, 2012.

K. N. Prasad, K. K. Nyati, A. Verma, A. Rizwan, and V. K. Paliwal, Tumor necrosis factor-alpha polymorphisms and expression This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. in Guillain-Barré syndrome, Hum Immunol, vol.71, pp.905-915, 2010.

R. Rivalino, D. Darmadi, and G. A. Siregar, Correlation between TNF-? and degree of gastritis, INA-JGHE, vol.19, pp.16-25, 2018.

S. Rossi, M. Cordella, and C. Tabolacci, TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness, J Exp Clin Cancer Res, vol.37, p.326, 2018.

C. Senthilkumar, S. Niranjali, V. Jayanthi, T. Ramesh, and H. Devaraj, Molecular and histological evaluation of tumor necrosis factor-alpha expression in Helicobacter pylori-mediated gastric carcinogenesis, J Cancer Res Clin Oncol, vol.137, pp.577-83, 2011.

C. Shih, Y. Lee, and H. Chiou, Association of TNF-alpha polymorphism with susceptibility to and severity of non-small cell lung cancer, Lung Cancer, vol.52, pp.15-20, 2006.

N. Stanilov, L. Miteva, Z. Dobreva, and S. Stanilova, Colorectal cancer severity and survival in correlation with tumour necrosis factor-alpha, Biotechnol Equip, vol.28, pp.911-918, 2014.

U. Thalmaier, N. Lehn, and K. Pfeffer, Role of tumor necrosis factor alpha in Helicobacter pylori gastritis in tumor necrosis factor receptor 1-deficient Mice, Infect Immun, vol.70, pp.3149-55, 2002.

H. Uysal, L. Chavez-galan, and D. Vesin, Transmembrane TNF and partially TNFR1 regulate TNFR2 expression and control inflammation in mycobacterial-induced pleurisy, Int J Mol Sci, vol.19, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02126567

H. Wajant, The role of TNF in cancer, Results Probl Cell Differ, vol.49, pp.1-15, 2009.

X. Wang and Y. Lin, Tumor necrosis factor and cancer, buddies or foes?, Acta Pharmacol Sin, vol.29, pp.1275-88, 2008.

Y. Y. Wang, G. H. Lo, and K. H. Lai, Increased serum concentrations of tumor necrosis factor-alpha are associated with disease progression and malnutrition in hepatocellular carcinoma, J Chin Med Assoc, vol.66, pp.593-601, 2003.

A. G. Wilson, J. A. Symons, T. L. Mcdowell, H. O. Mcdevitt, and G. W. Duff, Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation, Proc Natl Acad Sci U S A, vol.94, pp.3195-3204, 1997.

C. C. Wu, Y. K. Huang, and C. Y. Huang, Polymorphisms of TNF-? -308 G/A and IL-8 -251 T/A genes associated with urothelial carcinoma: A Case-Control Study, Bio Med Res Int, 2018.

T. Yamamoto, M. Kita, and T. Ohno, Role of tumor necrosis factor-alpha and interferon-gamma in Helicobacter pylori infection, Microbiol Immunol, vol.48, pp.647-54, 2004.

M. Yu, X. Zhou, and L. Niu, Targeting transmembrane TNF-? suppresses breast cancer growth, Cancer Res, vol.73, pp.4061-74, 2013.