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Journal articles
Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in Greater Lisbon, Portugal: Implications at the public health level
Abstract : Tuberculosis among foreign-born patients is a key indicator of country-level epidemiological profiles and, of an increasing concern in Europe given the more intensified migratory waves of refugees. Since Portugal presents a lower immigrant-associated TB incidence rate when compared to other European countries, we sought to characterize the epidemiology and transmission dynamics among the foreign-born population coming from Portuguese-speaking countries that are associated with higher TB incidences. In the present study we analyzed 133 Mycobacterium tuberculosis isolates obtained from foreign-born individuals over a three-year period in Lisbon, Portugal, using molecular epidemiological methods such as spoligotyping and 24-loci MIRU-VNTR. Moreover, all strains were subjected to drug susceptibility testing. The genetic profiles obtained suggest that strain importation from Portuguese speaking countries plays a less important role in TB epidemiology but instead argue in favor of a high degree of penetrance of Portuguese endemic strains to the migrant population, including multidrug resistant strains, which is particularly relevant to active screening programs.
https://hal-riip.archives-ouvertes.fr/pasteur-02950193
Contributor : Nalin Rastogi <>
Submitted on : Sunday, September 27, 2020 - 3:08:14 PM
Last modification on : Tuesday, September 29, 2020 - 3:05:53 AM
Contributor : Nalin Rastogi <>
Submitted on : Sunday, September 27, 2020 - 3:08:14 PM
Last modification on : Tuesday, September 29, 2020 - 3:05:53 AM