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Journal Articles Emerging Infectious Diseases Year : 2014

Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012

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Abstract

Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010-March 2012, rotavirus surveillance was conducted among 9,745 children <5 years of age in 14 hospitals/health centers in Niger, where rotavirus vaccine has not been introduced. Study participants had acute watery diarrhea and moderate to severe dehydration, and 20% of the children were enrolled in a nutrition program. Of the 9,745 children, 30.6% were rotavirus positive. Genotyping of a subset of positive samples showed a variety of genotypes during the first year, although G2P[4] predominated. G12 genotypes, including G12P[8], which has emerged as a predominant strain in western Africa, represented >80% of isolates during the second year. Hospitalization and death rates and severe dehydration among rotavirus case-patients did not differ during the 2 years. The emergence of G12P[8] warrants close attention to the characteristics of associated epidemics and possible prevention measures.
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pasteur-03238533 , version 1 (27-05-2021)

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Attribution - CC BY 4.0

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Anne-Laure Page, Viviane Jusot, Abdoul-Aziz Mamaty, Lagare Adamou, Jérôme Kaplon, et al.. Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012. Emerging Infectious Diseases, 2014, 20 (4), pp.573-580. ⟨10.3201/eid2004.131328⟩. ⟨pasteur-03238533⟩

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