Skip to Main content Skip to Navigation
Journal articles

SARS-CoV-2 antibody seroprevalence follow-up in Malagasy blood donors during the 2020 COVID-19 Epidemic

Abstract : Background: The incidence of the 2020 COVID-19 epidemic in Africa seems to be different from that of the rest of the world, however its true extent is probably underestimated. Conducting population based sero-surveys during the epidemic has moreover been extremely challenging, driving our group and others to study blood donor samples. Methods: We collected regional epidemiological COVID-19 surveillance data, and simultaneously monitored anti-SARS-CoV-2 antibody seroprevalences monthly throughout the epidemic in 5 major Region-associated Blood Transfusion Centres of Madagascar over a period of 9 months. Findings: Soon after attaining the first epidemic peaks between May and August 2020, both crude and population-weighted test-performance-adjusted seroprevalences of anti-SARS-CoV-2 antibodies was in Malagasy blood donors rapidly increased up to over 40% positivity. Interpretation: These findings suggest a high cumulative incidence of infection and seroconversion, which may have contributed to the observed deceleration of infection rates, but was not sufficient to prevent the second epidemic wave that struck Madagascar in Spring 2021.
Complete list of metadata

https://hal-riip.archives-ouvertes.fr/pasteur-03254611
Contributor : Philippe Dussart Connect in order to contact the contributor
Submitted on : Wednesday, June 9, 2021 - 7:31:10 AM
Last modification on : Tuesday, June 15, 2021 - 4:46:01 PM
Long-term archiving on: : Friday, September 10, 2021 - 6:05:52 PM

File

1-s2.0-S2352396421002127-main....
Publication funded by an institution

Licence


Distributed under a Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International License

Identifiers

Collections

Citation

Matthieu Schoenhals, Niry Rabenindrina, Jean Marius Rakotondramanga, Philippe Dussart, Rindra Randremanana, et al.. SARS-CoV-2 antibody seroprevalence follow-up in Malagasy blood donors during the 2020 COVID-19 Epidemic. EBioMedicine, Elsevier, 2021, 68, pp.103419. ⟨10.1016/j.ebiom.2021.103419⟩. ⟨pasteur-03254611⟩

Share

Metrics

Record views

80

Files downloads

17