First whole genome sequences and phylogenetic analysis of SARS-CoV-2 virus isolates during COVID-19 outbreak in Tunisia, North Africa.
Wasfi Fares
(1, 2)
,
Anissa Chouikha
(1, 2)
,
Kais Ghedira
(3)
,
Mariem Gdoura
(1, 2)
,
Dorra Rezig
(1, 2)
,
Sondes Haddad Boubaker
(1, 2)
,
Imene Ben Dhifallah
(1, 2)
,
Henda Touzi
(1, 2)
,
Walid Hammami
(1, 2)
,
Zina Meddeb
(1, 2)
,
Amel Sedraoui
(1, 2)
,
Nahed Hogga
(1, 2)
,
Imen Abouda
(1, 2)
,
Aurelia Kwasiborski
(4)
,
Veronique Hourdel
(4)
,
Guillain Mikaty
(4)
,
Valerie Caro
(4)
,
Jean Claude Manuguerra
(4)
,
Nissaf Ben Alaya
(5, 2)
,
Henda Triki
(1, 2)
1
Laboratoire de Virologie Clinique, Référence Régional OMS pour la Poliomyélite et la Rougeole - Laboratory of Clinical Virology, WHO Regional Reference Laboratory on Poliomyelitis and Measles
2 UTM - Université de Tunis El Manar
3 LR11IPT09 - Laboratoire de Bioinformatique, biomathématiques, biostatistiques (BIMS)
4 CIBU - Cellule d'Intervention Biologique d'Urgence (Centre National de Référence) - Laboratory for Urgent Response to Biological Threats (National Reference Center)
5 Ministère de la santé Publique [Tunisie]
2 UTM - Université de Tunis El Manar
3 LR11IPT09 - Laboratoire de Bioinformatique, biomathématiques, biostatistiques (BIMS)
4 CIBU - Cellule d'Intervention Biologique d'Urgence (Centre National de Référence) - Laboratory for Urgent Response to Biological Threats (National Reference Center)
5 Ministère de la santé Publique [Tunisie]
Wasfi Fares
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- Function : Correspondent author
- PersonId : 1124504
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Anissa Chouikha
- Function : Author
- PersonId : 772219
- ORCID : 0000-0002-0452-2856
Valerie Caro
- Function : Author
- PersonId : 747321
- IdHAL : valerie-caro
- ORCID : 0000-0001-8477-5708
Abstract
Full genomes sequences of six Tunisian SARS-CoV-2 strains were obtained from imported and locally transmission cases during the COVID-19 outbreak. Reported sequences were non-identical with 0.1% nucleotide divergence rate and clustered into 6 different clades with worldwide sequences. SNPs results favor the distribution of the reported Tunisian sequences into 3 major genotypes. These results indicate multiple introductions of the virus in Tunisia and add new genomic data on SARS-CoV-2 at the international level.